RCOG及Caprini评估模型预测产科住院患者静脉血栓栓塞症风险的效果研究

Effect of RCOG and Caprini Evaluation Model on Predicting the Risk of Venous Thromboembolism in Obstetric

目的探讨英国皇家妇产科医师学会(RCOG)发布的血栓风险评估模型和Caprini风险评估模型对预测产科住院患者静脉血栓栓塞症(VTE)的效果。方法采用回顾性病例对照研究,选取2019年1月-12月产科收治的39例VTE患者作为观察组,同时随机选取同时段同科室390例非VTE患者作为对照组。对两组患者分别用RCOG和Caprini风险评估模型进行回顾性血栓风险评分,比较两个模型预测VTE发生的效果。结果 Caprini模型评估患者产前、产后VTE风险等级差异有统计学意义(χ^2=321.09,P<0.05),RCOG模型评估患者产前、产后VTE风险等级差异有统计学意义(χ^2=40.93,P<0.05);RCOG模型和Caprini模型预测患者产前、产后VTE风险的ROC曲线下面积分别为0.57±0.05、0.69±0.05、0.69±0.04、0.81±0.03,差异有统计学意义(χ^2=40.93,P<0.05)。结论两种评估模型均能预测VTE发生,但RCOG较Caprini风险评估模型更适用于产科住院患者进行VTE风险评估。

Objective To investigate the efficacy of the thromboembolism risk assessment model and Caprini risk assessment model published by the royal college of obstetricians and gynaecologists(RCOG) in predicting venous thromboembolism(VTE) in obstetric inpatients. Methods A retrospective case-control study was conducted. Thirty-nine patients with VTE admitted to obstetrics from January to December 2019 were selected as the observation group, while 390 non-vte patients in the same department at the same time were randomly selected as the control group.The risk assessment models of RCOG and Caprini were used to evaluate the risk of thrombosis in two groups of patients. Results Caprini model showed statistically significant difference in risk level of prenatal and postnatal VTE in patients(χ^2=321.09,P<0.05), while RCOG model showed statistically significant difference in risk level of prenatal and postnatal VTE in patients(χ^2=40.93,P<0.05).The RCOG model and Caprini model predicted the area under the ROC curve of patients with prenatal and postnatal VTE risk as 0.57±0.05, 0.69±0.05, 0.69±0.04, and 0.81±0.03, respectively, with statistically significant differences(χ^2=40.93,P<0.05). Conclusion both assessment models can predict the occurrence of VTE, but RCOG risk assessment model is more suitable than Caprini risk assessment model for the risk assessment of VTE in obstetric inpatients.