PRP干预法对四肢粉碎性骨折患者术区恢复及肢体功能改善的作用分析

Effects of PRP intervention on the recovery of operative area and the improvement of limb function in patients with comminuted limb fracture after operation

目的研究富血小板血浆(PRP)干预法对四肢粉碎性骨折患者术区恢复及肢体功能改善的作用效果。方法四肢粉碎性骨折患者90例通过随机抽签法将其分为观察组和对照组,每组45例。对照组予以常规手术治疗,观察组则在对照组的基础上增用RPR干预。分别比较2组关节活动度,骨折愈合情况,术后不同时间点的Fernandez-Esteve骨痂评分、视觉模拟评分法(VAS)评分。结果观察组关节活动度优良率高于对照组(P<0.05)。观察组骨折愈合情况优于对照组,骨折愈合时间短于对照组(P<0.05)。观察组术后1、3、6、12个月时的Fernandez-Esteve骨痂评分均高于对照组(P<0.05)。观察组术后1、3、6、12个月时的VAS评分均低于对照组(P<0.05)。结论PRP干预法可促进四肢粉碎性骨折的术后恢复,改善肢体功能,减轻术后疼痛程度,值得临床推广应用。

Objective To investigate the effects of PRP intervention on the postoperative recovery and limb function improvement in patients with comminuted limb fractures after operation.Methods A total of 90 patients with comminuted limb fractures who were treated in our hospital from February 2016 to February 2018 were enrolled as research subjects,who were divided into observation group and control group by random lottery,with 45 cases in each group.The patients in control group received routine surgical treatment,however,the patients in observation group,on the basis of control group,were treated by RPR intervention.The range of motion of joints,fracture healing,Fernandez-Esteve eschar score and visual analogue score(VAS)score at different time points after operation were observed and compared between the two groups.Results The good/excellent rate of range of motion in observation group was significantly higher than that in control group(P<0.05).The fracture healing time in observation group was significantly shorter than that in control group(P<0.05).The Fernandez-Esteve eschar scores at 1m,3m,6m and 12m after operation in observation group were significantly higher than those in control group(P<0.05).Moreover the VAS scores at 1m,3m,6m and 12m after operation in observation group were significantly lower than those in control group(P<0.05).Conclusion PRP intervention can promote the postoperative recovery of patients with comminuted fracture of four limbs,improve limb function and reduce postoperative pain,therefor,which is worthy of clinical application and promotion.