弱视的神经影像学技术检查研究进展

Research progress of neuroimaging techniques examination of amblyopia

弱视的发病是由于视觉中枢的视功能受损,而当前弱视的临床检查以主观视功能检查为主,难以评估弱视发病的中枢病理机制。眼部超声、光学相干断层扫描(OCT)、功能近红外光谱(fNIRs)、磁共振(MRI)等影像学技术能够直观无创的检测眼部、视觉中枢的病理改变,为弱视的临床诊断及治疗提供了有效的神经影像学依据。本文对弱视的临床影像学检查的应用情况进行概述,并对弱视发病的中枢神经机制进行探讨,以期为弱视的诊断和临床研究提供依据。

The pathogenesis of amblyopia is due to impaired visual function of the visual center,and the current clinical examination of amblyopia is mainly subjective visual function,which is difficult to evaluate the pathogenesis of amblyopia of the central pathological mechanism.Ocular ultrasound,optical coherence tomography(OCT),functional near-infrared spectroscopy(fNIRs),magnetic resonance(MRI)and other neuroimaging technologies can detect pathological changes of the eye and visual center directly and noninvasively,which provides an effective neuroimaging basis for the clinical diagnosis and treatment of amblyopia.This paper reviewed the application of clinical neuroimaging examination of amblyopia,and explored the central nervous mechanism of amblyopia to provide basis for the diagnosis and clinical research of amblyopia.