改良标准外伤大骨瓣手术治疗基底节脑出血的研究

Modified Standard Traumatic Large Bone Flap Surgery for Basal Ganglia Cerebral Hemorrhage

目的探究基底节脑出血患者运用改良标准外伤大骨瓣手术治疗的临床价值。方法选取贵州省遵义市凤冈县人民医院2016年12月至2019年12月收治的基底节脑出血患者100例进行研究,随机数字表法分为观察组(50例)与对照组(50例),观察组运用改良标准外伤大骨瓣手术治疗,对照组运用小骨窗开颅显微手术治疗。对比两组实验室检查相关指标的改善、神经功能状况和并发症发生情况。结果治疗前,两组谷胱甘肽过氧化物酶、丙二醛、血清8-羟基脱氧鸟苷酸及格拉斯哥结局(GOS)评分各指标比较,差异无统计学意义(P>0.05);治疗后,观察组谷胱甘肽过氧化物酶、丙二醛、血清8-羟基脱氧鸟苷酸各指标水平均优于对照组(P<0.05);治疗后,观察组患者的GOS评分为(4.34±1.08)分高于对照组的(3.26±1.14)分,组间比较差异有统计学意义(P<0.05);观察组并发症发生率为10.00%,低于对照组的28.00%,组间比较差异有统计学意义(P<0.05)。结论基底节脑出血患者运用改良标准外伤大骨瓣手术治疗后,不仅能够有效提高治疗效果,恢复患者的各项实验室检查指标,还能够改善患者的神经功能,降低并发症发生率,具有较高的临床应用价值。

Objective To investigate the clinical value of basal ganglia cerebral hemorrhage patients with modified standard trauma large bone flap surgery.Methods 100 patients with basal ganglia cerebral hemorrhage admitted to Fenggang County People's Hospital in Zunyi City,Guizhou Province from December 2016 to December 2019 were randomly divided into an observation group(using modified standard traumatic large bone flap surgery)and a control group(using Small bone window craniotomy surgery),50 cases each.Compare the improvement of laboratoryrelated indicators,neurological status and complications in the two groups.Results Before treatment,the differences between the two groups of glutathione peroxidase,malondialdehyde,serum 8-hydroxydeoxyguanosine and GOS scores were not statistically significant(P>0.05).After treatment,the observation group Glutathione peroxidase,malondialdehyde,serum 8-hydroxydeoxyguanylic acid were better than the control group(P<0.05),and after treatment,the observation group had a high GOS score(4.34±1.08)Compared with the control group(3.26±1.14)points The difference was statistically significant(P<0.05),the incidence of complications in the observation group(10.00%)was lower than that in the control group(28.00%),the difference was statistically significant(P<0.05).Conclusion Patients with basal ganglia hemorrhage treated with modified standard large bone flap surgery can not only effectively improve the treatment effect,restore the patient's various laboratory indicators,but also improve the patient's neurological function and reduce the incidence of complications,it has high clinical application value.