ICU重症COPD合并呼吸衰竭的治疗及临床预后分析

Treatment and Clinical Prognosis of Severe COPD with Respiratory Failure in ICU

目的分析ICU重症慢性阻塞性肺疾病(COPD)合并呼吸衰竭的治疗及临床预后效果。方法选取2018年12月至2019年12月江苏省常州市904医院收治就诊的ICU重症COPD合并呼吸衰竭患者120例,按随机数字表法分为试验组和对照组,每组60例。对照组实施常规治疗,试验组实施有创与无创序贯通气治疗。比较两组患者的临床治疗效果、治疗前后指标、治疗不良反应的发生率及患者治疗前后的生活质量评分。结果试验组患者临床治疗效果显著优于对照组(P<0.05)。两组患者治疗前的各项指标比较差异无统计学意义(P>0.05),治疗后各项试验组指标显著优于对照组(P<0.05),同时试验组患者治疗不良反应发生率显著低于对照组(P<0.05),且两组患者治疗前生活质量评分比较差异无统计学意义(P>0.05)。治疗后生活质量评分比较,试验组显著优于对照组(P<0.05)。结论在ICU重症COPD合并呼吸衰竭患者的治疗中,实施有创与无创序惯性机械通气治疗效果显著优于常规治疗,患者治疗后的各项指标改善明显,临床预后效果明显,安全性更高。

Objective To analyze the treatment and clinical prognosis of severe COPD with respiratory failure in ICU.Methods Totally 120 ICU patients with severe COPD complicated with respiratory failure admitted to 904 Hospital of Changzhou City,Jiangsu Province from December 2018 to December 2019 were randomLy divided into experimental group and control group,with 60 cases in each group.The control group received routine treatment and the experimental group received non-invasive sequential ventilation.The clinical treatment effect,indexes before and after treatment,incidence of adverse events and quality of life of patients before and after treatment were compared Points.Results The clinical effect of the experimental group was significantly better than that of the control group(P<0.05).After treatment,the experimental group was significantly better than the control group(P<0.05),while the incidence of adverse events in the experimental group was significantly lower than that in the control group(P<0.05),and there was no difference between the two groups in the quality of life score before treatment(P>0.05),no statistical significance.After treatment,the quality of life score of the experimental group was significantly better than that of the control group(P<0.05).Conclusion In the treatment of severe COPD patients with respiratory failure in ICU,the effect of invasive and noninvasive sequential inertial mechanical ventilation is significantly better than that of conventional treatment.After treatment,the indicators of patients are improved significantly,and the clinical prognosis effect is obviously safe.Therefore,in the clinical treatment.