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阿托伐他汀联合曲美他嗪治疗冠心病的临床疗效观察

Effect of Atorvastatin Combined with Trimetazidine in Treatment of Coronary Heart Disease
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摘要 目的观察阿托伐他汀联合曲美他嗪治疗冠心病的临床疗效。方法选取2018年2月至2019年8月临沂市费县中医医院收治的75例冠心病患者为研究对象,随机数字表法分为对照组和观察组,对照组(36例)采用阿托伐他汀治疗,观察组(39例)采用阿托伐他汀联合曲美他嗪治疗。观察对比两组治疗疗效。结果观察组临床疗效97.43%,高于对照组83.33%,差异有统计学意义(P<0.05)。经治疗后观察组患者心绞痛发作次数少于对照组、心绞痛发作持续时间短于对照组(P<0.05)。经治疗后观察组患者心功能各指标改善情况优于对照组(P<0.05)。结论阿托伐他汀联合曲美他嗪治疗冠心病患可提高临床疗效、降低患者心绞痛发作、改善心功能。 Objective To analyze the clinical value of atorvastatin combined with trimetazidine in the treatment of coronary heart disease.Methods Totally 75 patients with coronary heart disease admitted to Fei County Traditional Chinese Medicine Hospital in Linyi City from February 2018 to August 2019 were selected as the research object.The control group(36 cases)was treated with atorvastatin.(39 cases)were treated with atorvastatin and trimetazidine.Observe and compare the therapeutic effect of the two groups.Results The clinical efficacy of the observation group was 97.43%,that of the control group was 83.33%(P<0.05).After treatment,the number of angina attacks in the observation group was less than that in the control group,and the duration of angina attacks was shorter than that in the control group(P<0.05).After treatment,the improvement of cardiac function in observation group was better than that in control group(P<0.05).Conclusion In patients with coronary heart disease,it is recommended to take atorvastatin combined with trimetazidine;it is of great value in improving clinical efficacy,reducing angina pectoris,improving heart function and endothelial function.
作者 余瑞华 YU Ruihua(Linyi Fei County Hospital of Traditional Chinese Medicine,Linyi,Shandong 273400,China)
出处 《大医生》 2020年第7期116-118,共3页 Doctor
关键词 冠心病 阿托伐他汀 曲美他嗪 coronary heart disease atorvastatin trimetazidine
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