肝静脉压力梯度对肝硬化临床终点事件的预测

Value of hepatic venous pressure gradient in predicting clinical end events in liver cirrhosis

肝硬化是肝脏疾病的终末阶段,失代偿期肝硬化以门静脉高压为显著特征,目前肝静脉压力梯度是评估门静脉高压的“金标准”,具有重要的临床意义。对肝静脉压力梯度在代偿期及失代偿期临床终点事件中的预测作用以及在门静脉高压药物治疗效果评价中的应用进行阐述,以期为临床早预测、早预防、早干预门静脉高压提供依据。

Liver cirrhosis is the end stage of liver disease,and decompensated liver cirrhosis has the significant feature of portal hypertension.At present,hepatic venous pressure gradient(HVPG)remains the“gold standard”for evaluating portal hypertension and thus has great significance in clinical practice.This article elaborates on the value of HVPG in predicting end events in compensated and decompensated liver cirrhosis and the application of HVPG in evaluating the therapeutic effect of drugs in the treatment of portal hypertension,so as to provide a basis for early prediction,early prevention,and early intervention of portal hypertension in clinical practice.