蒙药阿木日-6与比沙可啶对CT结肠成像前肠道准备的清洁作用

The cleaning effect of Mongolian medicine amuri-6 or bisacodyl on the preparation of CT colonography

目的:探讨分别应用蒙药阿木日-6与比沙可啶的肠道准备方案在CT结肠成像检查时的肠道清洁作用。方法:51例临床诊断为结直肠疾病或具有高发因素的患者在CT结肠成像前随机接受蒙药阿木日-6或比沙可啶结合碘钡联合造影的肠道准备方案,具体包括低渣饮食、口服蒙药阿木日-6或比沙可啶作为粪便软化剂、口服硫酸钡混悬液和碘海醇标记肠内残留物质,蒙药阿木日-6组和比沙可啶组分别为26例和25例。通过64排单源宝石能谱CT行腹部容积扫描,统计分析两组结直肠内残留液体评分、残留液体CT值以及残留粪便评分。结果:蒙药阿木日-6组中,61.54%(80/130)结直肠肠段没有残留液体,比沙可啶组为39.20%(49/125),差异有统计学意义(P<0.05);蒙药阿木日-6组、比沙可啶组肠内残留液体平均CT值分别为(2043±426)HU、(1795±379)HU,差异有统计学意义(P<0.05);蒙药阿木日-6组和比沙可啶组分别有76.92%和84.00%肠段内存在少量残留粪便,差异无统计学意义(P>0.05)。结论:相比比沙可啶,结合蒙药阿木日-6的肠道准备方案能够增加对肠内残留液体的清洁能力,但也会增加残留液体的CT值,而二者对于肠内残留粪便的清洁作用相似,蒙药阿木日-6具有更高的经济效益,是CT结肠成像前肠道准备较好的选择。

Objective:To analyze the cleaning effect of using Mongolian medicine amuri-6 or bisacodyl on the bowel preparation protocol before CT colonography.Methods:Fifty-one patients with clinical diagnosis of colorectal disease or high incidence factors were randomized to receive the bowel preparation of Mongolian medicine Amuri-6 or bisacodyl combined with iodine-barium labeling method before CT colonography examination,including a low residue diet, oral Mongolian medicine Amuri-6 or bisacodyl as a stool softener,oral barium sulfate suspension and iohexol for labeling colorectal residues.The Mongolian medicine Amuri-6 group and the bisacodyl group contained 26 and 25 subjects,respectively. The images were obtained by 64-row single-source Discovery CT. The colorectal residual fluid score,CT value of residual fluid,and residual stool score of the two groups were statistically analyzed.Results:In the Mongolian medicine amuri-6 group,61.54%(80/130)of patient’s colorectal segments had the best cleaning effect without any residual fluid,while the corresponding proportion of the bisacodyl group was 39.20%(49/125),the difference was statistically significant(P <0.05).The average CT values of colorectal residual fluid in Mongolian medicine Amuri-6 group and bisacodyl group were(2043±426)HU and(1795±379)HU,respectively,the difference was statistically significant(P<0.05).There was a small amount of colorectal residual stool of76.92% segments and 84.00% segments of Mongolian medicine amuri-6 group and bisacodyl group, respectively, the difference was not statistically significant(P >0.05). Conclusion:Compared with bisacodyl,the bowel preparation protocol combined with Mongolian medicine amuri-6 can increase the cleaning ability of colorectal residual liquid,but also increase the CT value of residual liquid.The cleaning effect of colorectal residual stool between twogroups is similar. Meanwhile,the Mongolian medicine amuri-6 has higher economic benefits, which is a better choice for bowel preparation before CT colonography.