眼球生物学测量参数与原发性闭角型青光眼的研究进展

Advances in the research on correlation between ocular biometry parameters and primary angle-closure glaucoma

原发性闭角型青光眼(PACG)是临床上常见的威胁视力的青光眼类型。PACG与正常人相比往往具有异常的眼部解剖结构。随着眼科影像学技术的发展,对于眼部生物学测量参数与PACG的发生和发展有了新的认识。周边前房深度、前房面积和体积、前房宽度、前房角参数、虹膜参数、晶状体厚度和位置、晶状体拱高、睫状体位置和厚度、脉络膜厚度等参数与PACG的发生密切相关,而角膜厚度、角膜曲率和角膜直径与PACG的关系有待进一步研究。眼部生物学测量参数的研究对于防治PACG具有重要的临床意义。

Primary angle-closure glaucoma(PACG)is one of the most common types of sight-threatening glaucoma.Patients with PACG often have abnormal ocular anatomical variations when compared to normal subjects.With the development of ophthalmic imaging technology,the knowledge is accumulating on the correlation between ocular biometric parameters and PACG pathogenesis and development.It is now known that parameters such as the anterior chamber(AC)depth,AC area,AC volume,AC width,AC angle parameters,iris parameters,lens thickness and positioning,lens vault,ciliary body positioning and thickness,and choroid thickness are all correlated with the pathogenesis of PACG.The associations between PACG and corneal thickness,corneal curvature and corneal diameter need to be further confirmed.Research on the ocular biometry measurement plays important role in the prevention and treatment of PACG.