乳糖酸阿奇霉素治疗小儿支气管炎的效果观察

Observation on the Effect of Azithromycin Lactobionate in the Treatment of Infantile Bronchitis

目的观察乳糖酸阿奇霉素治疗小儿支气管炎的临床疗效。方法选取2018年7月~2019年7月在我院诊治的106例小儿支气管炎患儿为研究对象,采用随机数字表法分为对照组和观察组,各53例。对照组采用红霉素治疗,观察组采用乳糖酸阿奇霉素治疗,比较两组临床治疗总有效率、临床症状(咳嗽、湿罗音、气促、哮鸣音)消失时间、住院时间、住院费用及临床不良反应。结果观察组治疗总有效率为94.33%,高于对照组的81.13%,差异有统计学意义(P<0.05);观察组咳嗽、湿罗音、哮鸣音消失时间均短于对照组,差异有统计学意义(P<0.05);观察组住院时间、住院费用均小于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论乳糖酸阿奇霉素治疗小儿支气管炎疗效理想,可在短时间内促进临床症状消退,促进患儿康复,进一步缩短住院时间,降低住院费用。同时临床不良反应少,应用安全可靠。

Objective To observe the clinical efficacy of azithromycin lactobionate in the treatment of infantile bronchitis.Methods A total of 106 children with infantile bronchitis who were diagnosed and treated in our hospital from July 2018 to July 2019 were selected as the research objects.They were divided into the control group and the observation group by random number table method,with 53 cases in each group.The control group was treated with erythromycin and the observation group was treated with azithromycin lactobionate.The total effective rate of clinical treatment,clinical symptoms(cough,wet rales,shortness of breath,wheezing)disappearance time,hospitalization time,hospitalization expenses and clinical adverse reactions.Results The total effective rate of treatment in the observation group was 94.33%,which was higher than 81.13%in the control group,the difference was statistically significant(P<0.05);The disappearance time of cough,wet rales,and wheezing in the observation group was shorter than that of the control group,the difference was statistically significant(P<0.05);the length of hospitalization and hospitalization expenses in the observation group were less than that of the control group,the difference was statistically significant(P<0.05);The incidence of adverse reactions in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion Azithromycin lactobionate had an ideal effect in the treatment of infantile bronchitis.It could promote the resolution of clinical symptoms in a short time,promote the recovery of the children,further shorten the length of hospitalization,and reduce the cost of hospitalization.At the same time,there were few clinical adverse reactions,and the application was safe and reliable.