孕前优生基层实验室室内质控调查与分析

Investigation and analysis of the internal quality control in primary clinical laboratory of pre-pregnancy eugenics

目的调查和分析江苏省孕前优生基层实验室临床检验室内质控的现状,探讨如何加强室内质控操作水平,提高孕前优生临床检验质量。方法收集2016-2017年96家基层孕前优生实验室的所有定性和定量检测项目的室内质控数据,分析室内质控上报情况、定量检测项目变异系数不合格情况及多个水平质控品使用情况。结果 2016、2017两年上报室内质控数据的实验室占比分别是71.88%、87.50%,其中上报定性项目的实验室只有34.38%、36.46%;两年中定量检测项目的上报率为63.30%、74.48%,定性检测项目的上报率为20.37%、24.49%;定量检测项目设定的变异系数不合格率分别是3.12%和3.06%,而当月实际检测的变异系数不合格率分别为2.72%、2.50%。结论加强基层实验室技术人员的专业培训,提高孕前优生临床检验室内质控操作技能;建立和完善临床检验质量管理机制,提高基层实验室室内质控数据的上报率、做到根据每月分析后得出的具体反馈建议进行整改,逐步提升基层实验室的临床检验质量。

Objective To investigate and analyze the current situation of quality control in primary Clinical Laboratory of Pre-pregnancy Eugenics of Jiangsu Province,and to explore how to strengthen the operation of internal quality control( IQC) for improving the laboratory quality. Methods The data of IQC of all qualitative and quantitative testing items of 96 Pre-pregnancy Eugenics laboratories from 2016 to2017 were collected and the reports situation of IQC,the unqualified coefficient of variation( CV) of quantitative testing items and the use of multiple levels of quality control products were analyzed. Results The percentage of laboratories reporting of IQC data in 2016 and 2017 were 71. 88% and 87. 50% respectively,with only 34. 38% and 36. 46% of qualitative items. The reporting rates of quantitative testing items were 63. 30% and 74. 48%,and of the qualitative testing items were 20. 37% and 24. 49% respectively. The expected rate of unqualified CV set by the quantitative test items were 3. 12% and 3. 06% respectively,while the actual rate were 2. 72% and 2. 50%. Conclusion It is necessary to strengthen the professional training of technicians and operation skills of IQC in primary laboratories of pre-pregnancy eugenics. By establishing and perfecting the quality management mechanism and improving the reporting rate of IQC,the primary laboratories could rectify according to the specific feedback monthly and improve the laboratory quality gradually.