超声探测甲状腺结节不同钙化模式与甲状腺癌的相关性

Correlation between Different Calcification Patterns of Thyroid Nodules and Thyroid Cancer

目的探讨甲状腺结节不同的钙化模式与甲状腺癌的相关性。方法回顾性分析2018年1月—2019年8月该院122例甲状腺结节伴钙化并行手术或穿刺活检的患者资料。观察结节内钙化的大小、多少、形态及分布状态特点,对比术后病理结果,探讨微钙化(长径<2 mm)、粗钙化(长径≥2 mm)、弧形钙化及混合型钙化与甲状腺癌的相关性。结果122例甲状腺结节伴钙化的患者中,75例术后病理诊断为甲状腺癌(包括乳头状癌、滤泡状癌、髓样癌),根据不同的钙化模式分类,伴微钙化的结节60例(占80.0%),伴粗钙化的结节10例(占13.3%),伴弧形钙化的结节1例(占1.3%),伴混合型钙化的结节4例(占5.3%)。结论微钙化与甲状腺癌关系最为密切,可作为诊断甲状腺癌的指标之一,但甲状腺癌也可以表现为不同的钙化模式,对钙化结节应给予高度的重视。

Objective To explore the correlation between different calcification patterns of thyroid nodules and thyroid cancer.Methods The data of 122 patients with thyroid nodules with calcification and concurrent surgery or biopsy were analyzed retrospectively from January 2018 to August 2019.Observe the size,amount,shape and distribution of calcification in the nodules,and compare the postoperative pathological results to explore microcalcification(long diameter<2 mm),coarse calcification(long diameter≥2 mm),arc calcification and mixed calcification and thyroid cancer relevance.Results Among the 122 patients with thyroid nodules and calcifications,75 cases were diagnosed with thyroid cancer(including papillary carcinoma,follicular carcinoma,and medullary carcinoma)after pathology.According to different calcification patterns,nodules with microcalcifications 60 cases(80.0%),10 cases with coarse calcification(13.3%),1 case with arc calcification(1.3%),4 cases with mixed calcification(5.3%).Conclusion Microcalcification is most closely related to thyroid cancer and can be used as one of the indicators for diagnosing thyroid cancer.However,thyroid cancer can also exhibit different calcification patterns,and high attention should be paid to calcified nodules.