二维斑点追踪评价糖尿病患者左房功能的价值

Evaluation of left atrial function in patients with diabetes by twodimensional speckle tracking imaging

目的应用二维斑点追踪(2D-STI)评价糖尿病患者左房功能,探讨其临床应用价值。方法选取单纯糖尿病患者25例(糖尿病组)、糖尿病性心肌病患者30例(DCM组)及健康志愿者20例(正常对照组)为研究对象,获取各组左房峰值应变(SS)、左房收缩期峰值应变率(s-SR)、左房舒张早期峰值应变率(e-SR)及舒张晚期峰值应变率(a-SR);使用Simpson法估测左房最大容积,结果进行对比分析。结果与正常对照组比较,糖尿病组和DCM组SS、s-SR、e-SR均减低,DCM组较糖尿病组减低更明显,差异均有统计学意义(均P<0.001);糖尿病组a-SR较DCM组和正常对照组均增高,DCM组高于正常对照组,差异均有统计学意义(均P<0.05)。结论2D-STI可以敏感地发现糖尿病患者左房功能的改变,具有较好临床应用价值。

Objective To investigate the changes of left atrial(LA)structure and function by two-dimensional speckle tracking imaging(2D-STI)in patients with diabetes,and to explore its clinical application value.Methods Twenty-five pure diabetes patients(diabete group),30 patients with diabetic cardiomyopathy(DCM group)and 20 cases of healthy subjects(control group)were included.All subjects were examined by 2D-STI to obtain the systolic strain and stain rate(SS,s-SR),early diastolic stain rate(e-SR)and late diastolic strain rate(a-SR).Left atrial maximum volume was measured by Simpson method,the results were compared and analyzed.Results Compared with the control group,SS,s-SR and e-SR were decreased in the diabete and DCM group,the decreasing of the DCM group were more obvious than those of diabete group(all P<0.001).a-SR of the diabete group was higher than that of other two groups,and a-SR of the DCM group was higher than that of control group,the difference were statistically significant(both P<0.05).Conclusion 2D-STI can effectively assess the LA function in patients with diabetes,which has important clinical application value.