婴儿Sweet综合征1例及RCM影像特征观察

Sweet's Syndrome in Infant:A Case Report and Imaging Characteristics of Reflectance Confocal Microscopy

患儿男,6个月,头面部、双上肢红斑、脓疱12 d。反射式共聚焦显微镜(RCM)检查示:棘层海绵水肿,可见脓疱样结构,真皮乳头水肿,真皮全层及毛囊周围可见大量高折光炎细胞浸润。皮损组织病理示:真皮浅中层水肿、中性粒细胞浸润及大量核尘,血管壁未见纤维蛋白样坏死。诊断:Sweet综合征。糖皮质激素治疗有效。

A 6-month-old boy presented abrupt onset of erythema and pustules on his face,head and arm for 12 days.RCM examination showed sponge edema,pustular and dermal papillary edema,a large number of hyper refractitis cells infiltrated around the dermis and hair follicles.Histopathologic examination showed the edema of upper dermis and a diffuse neutrophilic infiltration with nuclear dust in upper and middle dermis,it without fibrinoid necrosis in the vascular walls.The child was diagnosed as Sweet's syndrome.Glucocorticosteroid had a good effect.