血管治疗对颅内外动脉狭窄患者认知功能的影响

Effect of vascular therapy on cognitive function in patients with intracranial and extracranial artery stenosis

血管性认知功能障碍机制较为复杂,不仅与大血管病变引起的脑梗死相关,还与脑小血管病变、低灌注等因素相关。近年来研究表明血管治疗颅内外动脉狭窄,不仅能降低脑梗死的复发,同时还能改善患者的认知功能和生活质量。目前针对颅内外动脉狭窄患者治疗前后认知功能变化的研究受到广泛关注。该综述旨在归纳近年来的相关研究及进展,分析和总结颅内外动脉狭窄患者血管治疗术后认知变化及其影响机制。

Vascular cognitive impairment has a complex pathogenesis,which is not only related to cerebral infarction caused by macrovascular disease,but also related to the factors such as cerebral microvascular disease and hypoperfusion.Recent studies have shown that vascular therapy for intracranial and extracranial artery stenosis can reduce the recurrence of cerebral infarction and improve patients’cognitive function and quality of life.At present,the research on the change in cognitive function in patients with intracranial and extracranial artery stenosis after treatment has attracted more and more attention.This article reviews the research advances in recent years and analyzes and summarizes the change in cognitive function after vascular therapy and related influencing mechanism in patients with intracranial and extracranial artery stenosis.