胎粪吸入综合征新生儿心肌酶谱变化及应用磷酸肌酸疗效分析

Analysis of changes of neonatal myocardial enzyme with meconium aspiration syndrome and the efficacy in the application of creatine phosphate

目的:探讨胎粪吸入综合征新生儿心肌酶谱变化及应用磷酸肌酸钠治疗的临床效果。方法:2016年6月-2019年6月收治胎粪吸入综合征新生儿64例,随机分为两组,各32例。两组均采用常规治疗;对照组加用维生素C治疗;观察组在维生素C基础上加用磷酸肌酸治疗。比较两组临床疗效及心肌酶谱变化。结果:观察组治疗后心肌酶谱各项指标水平均优于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率明显高于对照组,差异有统计学意义(P<0.05)。结论:新生儿胎粪吸入综合征可引起心肌损害,应用磷酸肌酸钠治疗后,可有效降低心肌酶谱各项指标水平,疗效显著。

Objective:To explore the changes of neonatal myocardial enzyme with meconium aspiration syndrome and the clinical efficacy in the application of creatine phosphonic.Methods:From June 2016 to June 2019,64 newborns with meconium aspiration syndrome were selected and they were randomly divided into the two groups with 32 cases in each group.Conventional treatment was used in both groups.The control group was added in vitamin C to treatment,and the observation group was treated with creatine phosphonic on the basis of vitamin C.The clinical efficacy and changes of myocardial enzymes were compared between the two groups.Results:The various indicator levels of myocardial enzymes after treatment in the observation group were all better than the control group,the difference was statistically significant(P<0.05).The total effective rate of treatment in the observation group was significantly higher than the control group,the difference was statistically significant(P<0.05).Conclusion:Neonatal meconium aspiration syndrome can cause myocardial damage,and the application of creatine phosphate treatment can effectively reduce the various indicator levels of myocardial enzyme,and the effect is significant.