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去甲氧柔红霉素和柔红霉素治疗急性髓系白血病的效果和安全性观察 被引量:1

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摘要 目的观察急性髓系白血病患者使用去甲氧柔红霉素和柔红霉素的治疗效果和安全性。方法 40例急性髓系白血病患者,按照治疗手段不同分为对照组与观察组,各20例。对照组给予柔红霉素治疗,观察组给予去甲氧柔红霉素治疗。比较两组临床疗效、不良反应发生率。结果观察组患者治疗总有效率90.00%高于对照组的60.00%,差异有统计学意义(P<0.05)。观察组患者不良反应发生率为15.00%低于对照组的55.00%,差异有统计学意义(P<0.05)。结论相较于柔红霉素,去甲氧柔红霉素在治疗急性髓系白血病中能够取得更加明显的效果。不仅能够提高患者的治疗效果,而且不良反应发生率较少,具有较高的安全性,值得推广。
作者 张丽丽
出处 《中国实用医药》 2020年第25期142-144,共3页 China Practical Medicine
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  • 1赵桂兰.去甲氧柔红霉素治疗难治性急性髓系白血病的疗效分析[J].内蒙古医学院学报,2005,27(5):36-37. 被引量:4
  • 2张立冬.4-去甲氧柔红霉素在白血病治疗中的应用[J].中华血液学杂志,1995,16(2):99-102. 被引量:13
  • 3钱思轩,李建勇,陆化,徐卫,陈丽娟,张苏江,吴汉新,盛瑞兰.标准剂量去甲氧柔红霉素联合阿糖胞苷治疗急性髓细胞白血病[J].临床血液学杂志,2007,20(2):67-70. 被引量:3
  • 4Cheson BD, Bennett JM, Kopecky KJ, et al. Revised recommendations of the International Working Group for diagnosis, standardization of response criteria, treatment outcomes, and reporting standards for therapeutic trials in acute myeloid leukemia. J Clin Oncol, 2003 ;21:4642 -4649.
  • 5Grimwade D, Walker H, Oliver F, et al. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 Trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood, 1998 ;92 : 2322 - 2333.
  • 6Berman E, Heller G, Santorsa J, et al. Results of a randomized trial comparing idarubicin and cytosine arabinoside with daunorubicin and cytosine arabinoside in adult patients with newly diagnosed acute myelogenous leukemia. Blood, 1991 ;77 : 1666 -1674.
  • 7Koistinm P, Raty R, Itala M, et al. Long-term outcome of intensive chemotherapy for adults with de nono acute myeloid leukemia (AML) : the nationwide AML-92 study by the Finnish Leukaemia Group. Eur J Haematol, 2007 ;78:477 -486.
  • 8No authors listed. A systematic collaborative overview of randomized trials comparing idarubicin with daunorubicin (or other anthracyclines) as induction therapy for acute myeloid leukaemia. AML Collaborative Group. Br J Haematol, 1998 ;103:100 - 109.
  • 9Flasshove M, Meusers P, Schutte J, et al. Long-term survival after induction therapy with idarubicin and cytosine arabinoside for de novo acute myeloid leukemia. Ann Hematol, 2000 ;79:533 -542.
  • 10Masaoka T,Agawa M,Yamade K,et al.A phase2comparative of idarubicin plus cytarabine versus dauno rubicin plus cy2tarabine in adult acute myeloid leukemia[J].Sem in Hematol,1996,33(Supp l3):12-17.

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