支链氨基酸对动物糖脂代谢的调控及作用机理

Regulation and Mechanism of Branched-Chain Amino Acids on Animal Glycolipid Metabolism

动物的糖脂代谢维持着机体的能量平衡,若糖脂代谢紊乱则可能引发一系列代谢病症,如肥胖、胰岛素抵抗等。近年来的研究发现,支链氨基酸作为营养物质和信号分子可以调控动物机体的糖脂代谢,这为预防和治疗糖脂代谢相关性疾病提供了新的思路,也可为畜牧生产的营养调控提供参考。本文主要概括了支链氨基酸对糖脂代谢有何影响,并阐述其调控机理。

Energy balance is maintained by animal glycolipid metabolism,the disorder of which cause a series of metabolic disorders,including obesity and insulin resistance.Recent studies have showed that branched-chain amino acids regulate glycolipid metabolism in animals as nutrients or signal molecules,which provides new ideas for the prevention and treatment of glycolipid metabolism-related diseases and references for application in livestock production.This article mainly summarizes the influence of branched-chain amino acids on glycolipid metabolism and elaborates its mechanism.