慢性萎缩性胃炎辨证分型与HP感染的相关性研究

Study on the Correlation between Traditional Chinese Medicine Syndrome Differentiation and HP Infection in Patients with Chronic Atrophic Gastritis

目的探讨慢性萎缩性胃炎患者中医辨证分型与幽门螺杆菌(HP)感染的相关性。方法选取慢性萎缩性胃炎患者300例,其中肝胃气滞型50例,脾胃虚寒型48例,胃阴不足型60例,脾胃湿热型45例,肝胃郁热型42例,胃络瘀血型55例。结果慢性萎缩性胃炎中医证型分布情况,胃阴不足型(20.00%)>胃络瘀血型(18.33%)>肝胃气滞型(16.67%)>脾胃虚寒型(16.00%)>脾胃湿热型(15.00%)>肝胃郁热型(14.00%);慢性萎缩性胃炎性别分布情况,女性(51.67%)发病率高于男性(48.33%);慢性萎缩性胃炎各证型与Hp感染的关系,感染率从高到低依次为脾胃虚寒型(83.33%)、胃络瘀血型(81.82%)、胃阴不足型(80.00%)、肝胃气滞型(72.00%)、肝胃郁热型(71.42%)、脾胃湿热型(71.11%)。结论慢性萎缩性胃炎的主要中医证型为胃阴不足型、胃络瘀血型、肝胃气滞型和脾胃虚寒型,Hp感染率较高的中医证型为脾胃虚寒、胃络瘀血型、胃阴不足型和肝胃气滞型,女性发病率高于男性。

Objective To explore the correlation between TCM syndrome differentiation and HP infection in patients with chronic atrophic gastritis.Methods 300 cases of chronic atrophic gastritis were collected,including 50 cases of liver-stomach qi stagnation type,48 cases of Spleen-stomach deficiency cold type,60 cases of stomach yin deficiency type,45 cases of Spleen-stomach dampness-heat type,42 cases of liver-stomach stagnation-heat type and 55 cases of stomach collateral stasis-blood type.Results Distribution of TCM syndromes of chronic atrophic gastritis:deficiency of stomach yin(20.00%)>stagnation of stomach collaterals(18.33%)>stagnation of liver and stomach qi(16.67%)>deficiency of spleen and stomach(16.00%)>damp-heat of spleen and stomach(15.00%)>stagnation of liver and stomach(14.00%).The sex distribution of chronic atrophic gastritis was higher in women(51.67%)than in men(48.33%).The relationship between each syndrome type of chronic atrophic gastritis and Hp infection was in the order of Spleen-stomach deficiency cold type(83.33%),stomach collateral stasis blood type(81.82%),stomach yin deficiency type(80.00%),liver-stomach qi stagnation type(72.00%),liver-stomach stagnation heat type(71.42%)and spleen-stomach dampness-heat type(71.11%).Conclusion The main TCM syndromes of chronic atrophic gastritis are deficiency of stomach yin,stasis of stomach collaterals and blood,stagnation of liver and stomach qi and deficiency of spleen and stomach cold.The TCM syndromes with high infection rate of Hp are deficiency of spleen and stomach cold,stagnation of stomach collaterals and blood,deficiency of stomach yin and stagnation of liver and stomach qi.The incidence of female is higher than that of male.