早期康复训练与延迟活动在醒脑开窍汤治疗急性脑梗死中的效果及对MDA、TNF-α水平的影响

Effect of Early Rehabilitation Training and Delayed Activity on the Treatment of Acute Cerebral Infarction by Xingnao Kaiqiao Decoction and Its Influence on MDA and TNF-αlevel

目的研究早期康复训练与延迟活动在醒脑开窍汤治疗急性脑梗死中的效果及对MDA、TNF-α水平的影响。方法选取80例收治的急性脑梗死患者,随机分为试验组和对照组,各40例。2组均使用常规方法联合醒脑开窍汤治疗,对照组进行延迟活动,实验组进行早期康复训练,比较2组治疗后临床有效率;MDA、TNF-α水平、FMA、MBI、MMSE的变化以及不良反应发生率。结果试验组的有效率为95.00%,高于对照组的72.50%;与对照组相比,治疗后试验组的MDA、TNF-α水平较低、FMA、MBI、MMSE评分较高(P<0.05);2组不良反应发生率无明显差异(P>0.05)。结论醒脑开窍汤联合早期康复训练可以有效减轻急性脑梗死患者的炎症反应、提高神经功能和日常生活能力,且效果显著优于延迟活动,值得推广应用。

Objective To study the effect of early rehabilitation training and delayed activity on the treatment of acute cerebral infarction by Xingnao Kaiqiao decoction and its effect on MDA and TNF-αlevels.Methods 80 patients with acute cerebral infarction admitted to our hospital were randomly divided into experimental group and control group,each with 40 cases.The two groups were treated with conventional methods combined with xingnaokaiqiao decoction,the control group received delayed activities,and the experimental group received early rehabilitation training.The clinical efficiency of the two groups after treatment,changes of MDA,TNF-α,FMA,MBI,MMSE and incidence of adverse reactions was compared.Results The effective rate of the experimental group was 95.00%,compared with 72.50%of the control group.Compared with the control group,MDA,TNF-α,FMA,MBI and MMSE scores were lower in the experimental group after treatment(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Xingnao Kaiqiao decoction combined with early rehabilitation training can effectively reduce the inflammatory response of patients with acute cerebral infarction,improve neurological function and daily living ability,and the effect is significantly better than delayed activity,which is worthy of promotion and application.