霍夫曼消除法合成丁二烯的研究

Synthesis of Butadiene by Hoffmann Elimination Method

依托我国丰富的煤炭资源,以煤焦油中的吡咯烷为原料,采用霍夫曼消除法合成丁二烯。通过对反应溶剂、碱种类、反应时间、温度四个因素进行考察,综合对比分析最终确定较优的反应体系为:采用H2O为溶剂,NaOH提供碱性环境,反应温度为80℃,反应时间为9h,在此反应条件下能源和时间成本是最低的,此时丁二烯的收率达到25.12%。

Relying on my country’s rich coal resources,pyrrolidine in coal tar is used as the raw material to synthesize butadiene by Huffman elimination method.Through the investigation of the four factors of reaction solvent,alkali type,reaction time and temperature,comprehensive comparative analysis finally determined that the better reaction system is:using H2O as the solvent,NaOH provides an alkaline environment,the reaction temperature is 80℃,and the reaction time is 9h,the energy and time costs are the lowest under this reaction condition,but the yield of butadiene reaches 25.12%.