期刊文献+

PCT、hs-CRP及WBC水平在新生儿细菌性感染疾病中的诊断价值 被引量:3

下载PDF
导出
摘要 目的:分析血清降钙素原(PCT)、超敏C反应蛋白(hs-CRP)、白细胞计数(WBC)水平对新生儿细菌性感染的诊断价值。方法:将某院新生儿科收治的77例细菌性感染新生儿作为感染组,根据感染程度分为重症感染组30例、非重症感染组47例,另筛选同期在本院出生的30例健康新生儿作为对照组。采集静脉血检测比较新生儿入院时、治疗72 h血清PCT、hs-CRP及WBC水平。结果:入院时细菌性感染患儿血清PCT、hs-CRP、WBC均显著高于对照组;且重症感染组血清PCT、hs-CRP、WBC显著高于非重症感染组(P<0.05);与治疗前比较,治疗72h后患儿血清PCT、hs-CRP、WBC均显著下降(P<0.05),但重症感染组仍高于非重症感染组(P<0.05);PCT单一指标预测重症细菌性感染的敏感度、特异度分别为86.70%、100.00%,联合诊断敏感度、特异度为93.30%、98.70%。结论:新生儿细菌性感染治疗前后血清PCT、hs-CRP及WBC水平变化显著,联合诊断重症细菌性感染的效能最佳,值得临床重视。
作者 郭小旦
出处 《淮海医药》 CAS 2020年第4期371-374,共4页 Journal of Huaihai Medicine
  • 相关文献

参考文献12

二级参考文献94

  • 1王晓蕾.新生儿感染病原菌与抗菌药物耐药现状[J].儿科药学杂志,2007,13(3):5-8. 被引量:8
  • 2AHMED I, GHAAFOOR T, WAGAN T, et al. Diagnostic valae of C- reactive protein and heamatological parameters in neonatal sepsis[J]. J Coll Physicians Surg Park, 2005, 15(3): 152-156.
  • 3Kumar R,Musoke R,Macharia WM,et al.Validation of c-reac-tive protein in the early diagnosis of neonatal sepsis in a tertiary care hospital in Kenya[J].East Afr Med J,2010,87(6):255-261.
  • 4Hangai S,Nannya Y,Kurokawa M.A role of procalcitonin and C-reactive protein for the discrimination between tumor fever and infection in patients with hematological diseases[J].Leuk Lymphoma,2014,2(3):1-17.
  • 5Lin KH,Wang FL,Wu MS,et al.Serum procalcitonin and C-reactive protein levels as markers of bacterial infection in patients with liver cirrhosis:a systematic review and meta-analysis[J].Diagn Microbiol Infect Dis,2014,21(2):856.
  • 6Kuo KC,Huang YH,Chen IL,et al.Are antibiotics beneficial to children suffering from enterovirus infection complicated with a high C-reactive protein level[J].Int J Infect Dis,2011,12(2):89-92.
  • 7Ryder E,Diez-Ewald M,Mosquera J,et al.Association of obesity with leukocyte count in obese individuals without metabolic syndrome[J].Diabetes Metab Syndr,2014,8(4):197-204.
  • 8Orouji E,Ziegler B,Umansky V,et al.Leukocyte count restoration under dabrafenib treatment in a melanoma patient with vemurafenib-induced leukopenia:case report[J].Medicine(Baltimore),2014,93(28);e161.
  • 9Tenorio T R,Farah B Q,Ritti-Dias R M,et al.Relation between leukocyte count,adiposity,and cardiorespiratory fitness in pubertal adolescents[J].Einstein(Sao Paulo),2014,12(4):420-424.
  • 10Schützle H,Forster J,Superti-Furga A,et al.Is serum procalcitonin a reliable diagnostic marker in children with acute respiratory tract infections?:a retrospective analysis[J].Eur J Pediatr,2009,168(9):1117-1124.

共引文献619

同被引文献35

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部