摘要
目的分析呼吸道感染儿童9项呼吸道感染病原体血清免疫球蛋白M(IgM)抗体检测结果。方法选取200例呼吸道感染患儿为研究对象。采集患儿入院当日外周静脉血,采用间接免疫荧光法检测血清9项呼吸道感染病原体IgM抗体。结果200例患儿中,63例检测到病原体(31.50%),其中1种病原体感染者49例(77.78%),2种病原体混合感染者12例(19.05%),3病原体混合感染者2例(3.17%);最常见的病原体感染是肺炎支原体(MP)感染(42例)、乙型流感病毒(IFFBV)感染(10例)。女患儿病原体阳性率为47.56%,显著高于男患儿的20.34%(P<0.05)。学龄前组、学龄组患儿病原体阳性率显著高于婴儿组、幼儿组(P<0.05)。春季组患儿病原体阳性率为58.93%,显著高于夏季组的22.92%、秋季组的22.00%、冬季组的17.39%(P<0.05)。结论MP和IFFBV是儿童呼吸道感染的主要病原体,且呼吸道病原体的流行与患儿性别、年龄及季节均密切相关。
Objective To analyze the detection results of serum immunoglobulin M(IgM)antibody of 9 pathogens of respiratory tract infection in children.Methods A total of 200 children with respiratory tract infection were selected as the research objects.Peripheral venous blood was collected on the day of hospital admission,and serum IgM antibody of 9 pathogens of respiratory tract infection was detected by indirect immunofluorescence method.Results Among 200 cases,pathogens were detected in 63 cases(31.50%),including 49 cases(77.78%)of one pathogen infection,12 cases(19.05%)of mixed infection of two pathogens,and 2 cases(3.17%)of mixed infection of three pathogens.The most common pathogens were mycoplasma pneumoniae(MP)infection(42 cases)and influenza B virus(IFFBV)infection(10 cases).The positive rate of pathogens in female children was 47.56%,which was significantly higher than 20.34%in male children(P<0.05).The positive rates of pathogens in the pre-school group and the school-age group were significantly higher than those in the infant group and the young children group(P<0.05).The positive rate of pathogens in the spring group was 58.93%,which was significantly higher than 22.92%in the summer group,22.00%in the autumn group and 17.39%in the winter group(P<0.05).Conclusion MP and IFFBV are the main pathogens of respiratory tract infection in children,and the prevalence of respiratory pathogens is closely related to children′s gender, age and the season.
作者
马爱婷
郭艳红
MA Aiting;GUO Yanhong(Department of Pediatrics,Wubu County hospital in Yulin City,Yulin,Shaanxi,718200;Department of Neonatology,Fugu County People′s Hospital,Yulin,Shaanxi,719499)
出处
《实用临床医药杂志》
CAS
2020年第14期90-93,共4页
Journal of Clinical Medicine in Practice
基金
陕西省自然科学基金资助项目(2017JM8062)。
关键词
呼吸道感染
儿童
病原体
免疫球蛋白M抗体
肺炎支原体
乙型流感病毒
respiratory tract infection
children
pathogen
immunoglobulin M antibody
mycoplasma pneumoniae
influenza B virus