呼吸道感染患儿9项呼吸道感染病原体血清IgM抗体检测200例分析

Analysis in detection results of serum IgM antibody of 9 pathogens of respiratory tract infection in 200 children

目的分析呼吸道感染儿童9项呼吸道感染病原体血清免疫球蛋白M(IgM)抗体检测结果。方法选取200例呼吸道感染患儿为研究对象。采集患儿入院当日外周静脉血,采用间接免疫荧光法检测血清9项呼吸道感染病原体IgM抗体。结果200例患儿中,63例检测到病原体(31.50%),其中1种病原体感染者49例(77.78%),2种病原体混合感染者12例(19.05%),3病原体混合感染者2例(3.17%);最常见的病原体感染是肺炎支原体(MP)感染(42例)、乙型流感病毒(IFFBV)感染(10例)。女患儿病原体阳性率为47.56%,显著高于男患儿的20.34%(P<0.05)。学龄前组、学龄组患儿病原体阳性率显著高于婴儿组、幼儿组(P<0.05)。春季组患儿病原体阳性率为58.93%,显著高于夏季组的22.92%、秋季组的22.00%、冬季组的17.39%(P<0.05)。结论MP和IFFBV是儿童呼吸道感染的主要病原体,且呼吸道病原体的流行与患儿性别、年龄及季节均密切相关。

Objective To analyze the detection results of serum immunoglobulin M(IgM)antibody of 9 pathogens of respiratory tract infection in children.Methods A total of 200 children with respiratory tract infection were selected as the research objects.Peripheral venous blood was collected on the day of hospital admission,and serum IgM antibody of 9 pathogens of respiratory tract infection was detected by indirect immunofluorescence method.Results Among 200 cases,pathogens were detected in 63 cases(31.50%),including 49 cases(77.78%)of one pathogen infection,12 cases(19.05%)of mixed infection of two pathogens,and 2 cases(3.17%)of mixed infection of three pathogens.The most common pathogens were mycoplasma pneumoniae(MP)infection(42 cases)and influenza B virus(IFFBV)infection(10 cases).The positive rate of pathogens in female children was 47.56%,which was significantly higher than 20.34%in male children(P<0.05).The positive rates of pathogens in the pre-school group and the school-age group were significantly higher than those in the infant group and the young children group(P<0.05).The positive rate of pathogens in the spring group was 58.93%,which was significantly higher than 22.92%in the summer group,22.00%in the autumn group and 17.39%in the winter group(P<0.05).Conclusion MP and IFFBV are the main pathogens of respiratory tract infection in children,and the prevalence of respiratory pathogens is closely related to children′s gender, age and the season.