自拟解毒消痈汤联合敛疮生肌散外用治疗术后肛周脓肿的效果观察

Effect of self-made Jiedu Xiaoyong Decoction combined with external use of Lianchuang Shengji Powder in treatment of perianal abscess patients after surgery

目的观察自拟解毒消痈汤联合敛疮生肌散外用治疗术后肛周脓肿的效果。方法将收治的80例接受肛周脓肿手术患者分为对照组和研究组,每组40例。对照组患者接受常规抗生素联合莫匹罗星外用治疗,研究组患者接受自拟解毒消痈汤加减口服联合敛疮生肌散外用治疗。观察临床总有效率、临床表现评分、血清炎症因子、免疫功能指标及肛门功能指标。结果研究组临床治疗总有效率高于对照组,差异有统计学意义(P<0.05);研究组的白细胞介素-6(IL-6)、白细胞介素-8(IL-8)和肿瘤坏死因子-α(TNF-α)等血清炎症因子水平均低于对照组,差异有统计学意义(P<0.05);研究组患者的肛管静息压、肛管最大收缩压高于对照组,而大便失禁严重度评分(Wexner评分)低于对照组,差异有统计学意义(P<0.05)。结论自拟解毒消痈汤联合敛疮生肌散外用可有效缓解肛周脓肿术后患者的肛门疼痛,减轻炎症反应,加快创口愈合,促进肛门功能恢复。

Objective To observe effect of self-made Jiedu Xiaoyong Decoction combined with external use of Lianchuang Shengji Powder in treatment of perianal abscess patients after surgery.Methods A total of 80 patients with perianal abscess after surgery were divided into control group and study group,with 40 cases in each group.The patients in the control group received conventional antibiotics and mupiroxine external treatment,while the patients in the study group received self-made Jiedu Xiaoyong Decoction combined with external use of Lianchuang Shengji Powder for treatment.Total clinical efficacy rate,clinical performance score,serum inflammatory factors,immune function indicators and anal function indicators were observed.Results The total efficacy rate of clinical treatment in the study group was significantly higher than that in the control group(P<0.05).The levels of interleukin-6(IL-6),interleukin-8(IL-8)and tumor necrosis factor-α(TNF-α)in the study group were significantly lower than those in the control group(P<0.05);the anal resting pressure and maximum anal systolic pressure of patients in the study group were significantly better than those in the control group,while the severity score of fecal incontinence(Wexner score)was significantly lower than that in the control group(P<0.05).Conclusion Self-made Jiedu Xiaoyong Decoction combined with external use of Lianchuang Shengji Powder can effectively relieve anal pain of patients after perianal abscess operation,reduce inflammatory response,accelerate wound healing and promote anal function recovery.