基于指南研究和评估工具Ⅱ的妊娠期高血压指南评价及内容比较

Quality assessment on clinical practice guidelines for hypertensive disorders of pregnancy with the Appraisal of Guidelines for Research and EvaluationⅡInstrument

目的探讨国内外妊娠期高血压相关指南的现状及质量,为优化临床实践指南提供参考。方法用指南研究和评估工具(AGREE)Ⅱ对16部妊娠期高血压指南的质量进行评价分析,并对推荐主要内容进行比较分析。结果英国国家卫生与临床优化研究所(NICE)与新西兰指南为A级,中华与澳大利亚和新西兰产科学会(SOMANZ)指南推荐级别为C级,其余指南为B级。拉贝洛尔和硝苯地平被推荐为一线降压药,阿司匹林和钙剂作为预防药物被推荐,但各个指南的推荐内容略有不同。结论指南整体质量较高,但在严谨性方面仍需要进一步优化质量。

Objective To discuss and analyze the current status and the quality of guidelines for hypertensive disorders of pregnancy at home and abroad,which would improve the quality of clinical practice guidelines.Methods The Appraisal of Guidelines for Research and Evaluation(AGREE)ⅡInstrument was applied to evaluate the quality of related 16 guidelines and to compare the main recommendations.Results The recommendation level of the National Institute for Health and Care Excellence(NICE)and New Zealand is grade A,China and the Society of Obstetric Medicine of Australia and New Zealand(SOMANZ)is grade C,the others is grade B.Labetalol and nifedipine are recommended as first-line antihypertensive drugs,and aspirin and calcium agents are recommended as preventive drugs,but the detailed recommendations are slightly different.Conclusion The overall quality of the included guidelines is high,but it still needs to be further optimized in the rigor of development.