ST段抬高性心肌梗死患者院前急救时应用抗血小板治疗对近期心血管事件的预防作用

Preventive Effect of Antiplatelet Therapy on Recent Cardiovascular Events in Patients with ST-segment Elevation Myocardial Infarction

目的探讨抗血小板治疗应用于ST段抬高型心肌梗死患者治疗中的临床效果。方法将2017年3月-2019年3月收治的63例ST段抬高型心肌梗死患者作为研究对象,根据治疗方法将对象分为观察组(n=32)和对照组(n=31),对照组给予常规院前急救,观察组在此基础上加入抗血小板治疗,比较两组的救治效果。结果两组治疗后的心功能指标均有所改善,但组间比较观察组均优于对照组,各数据组间差异有统计学意义(P<0.05);随访6个月显示:观察组心血管事件发生率为6.25%(2/32),对照组心血管事件发生率为22.58%(7/31),组间差异有统计学意义(χ2=4.808,P<0.05);两组治疗期间的不良反应发生率比较,差异无统计学意义(P>0.05)。结论在ST段抬高型心肌梗死患者的院前救治中加入抗血小板治疗,可有效改善患者的心功能并降低近期心血管事件的发生,治疗方法临床价值显著。

Objective To investigate the clinical effect of antiplatelet therapy in the treatment of patients with ST-segment elevation myocardial infarction.Methods Sixty-three patients with ST-segment elevation myocardial infarction admitted from March 2017 to March 2019 were selected as the research objects.According to the treatment methods,the subjects were divided into observation group(n=32)and control group(n=31).The control group was given routine pre-hospital first aid,and the observation group was added antiplatelet therapy on this basis to compare the rescue effects of the two groups.Results The cardiac function indexes of the two groups had improved after treatment,but the observation group was better than the control group in comparison between the groups,and the difference between the data groups was statistically significant(P<0.05);follow-up for six months shows:the incidence of cardiovascular events in the observation group was 6.25%(2/32),and the incidence of cardiovascular events in the control group was 22.58%(7/31).There was a statistically significant difference between the two groups(χ2=4.808,P<0.05);There was no statistical significant difference in the incidence of adverse reactions during the treatment period(P>0.05).Conclusion Adding antiplatelet therapy to the prehospital treatment of patients with ST-segment elevation myocardial infarction can effectively improve the patient's cardiac function and reduce the occurrence of recent cardiovascular events.The clinical value of the treatment method is significant.