三维适形调强放射治疗老年食道癌患者的疗效与安全性评估

Evaluation of the Efficacy and Safety of Three-dimensional Conformal Intensity-modulated Radiotherapy in Elderly Patients with Esophageal Cancer

目的研究应用三维适形调强放射治疗食道癌老年患者的效果和安全性。方法随机选取在2015年1月-2018年12月期间在该院接受治疗的92例食道癌老年患者,将其作为研究对象,并采取随机分组的方式分为对照组和观察组,每组46例。对对照组老年患者采取常规的放射治疗,对观察组老年患者应用三维适形调强放射治疗,对比两组老年患者接受不同治疗方式进行治疗后的疗效,同时将两组老年患者接受治疗后的不良反应情况进行比较。结果观察组老年患者接受治疗后的总有效率为95.7%,高于对照组的80.4%;观察组老年患者在接受治疗后的不良反应发生率为8.7%,低于对照组的32.6%(χ^2=8.026,P<0.05)。结论对食道癌老年患者应用三维适形调强放射治疗的效果显著,不良反应情况少,具有较高的安全性。

Objective To study the effect and safety of three-dimensional conformal intensity-modulated radiotherapy in elderly patients with esophageal cancer. Methods A total of 92 elderly patients with esophageal cancer who were treated in the hospital from January2015 to December 2018 were randomly selected. They were selected as the research object and randomly divided into control group and observation group. 46 cases each. The elderly patients in the control group were treated with conventional radiotherapy, and the elderly patients in the observation group were treated with three-dimensional conformal intensity-modulated radiotherapy. The cura-tive effects of the two groups of elderly patients received different treatment methods were compared. Compare adverse reactions. Re-sults The total effective rate of elderly patients in the observation group after receiving treatment was 95.7%, which was higher than80.4% in the control group;the adverse reaction rate of elderly patients in the observation group after receiving treatment was 8.7%,which was lower than 32.6% in the control group(χ~2=8.026, P<0.05). Conclusion The effect of three-dimensional conformal intensitymodulated radiotherapy on elderly patients with esophageal cancer is significant, with few adverse reactions, and high safety, which is worthy of promotion.