酒精依赖患者心电图的变化及危险因素分析

Analysis of ECG Changes and Risk Factors in Patients with Alcohol Dependence

目的研究酒精依赖患者心电图的变化情况并分析其相关危险因素。方法选取2017年4月—2019年4月该院收治的酒精依赖患者110例进行研究,记为研究组。另取同期于该院进行体检的正常人员100名记为对照组。分别对比分析两组人员心电图变化情况(主要涵盖ST-T改变、左心室高电压、窦性心律失常、期前收缩以及传导阻滞等),并分析饮酒史时间长短以及日饮酒量对心电图改变的影响,予以多因素Logistic回归分析。结果研究组心电图异常发生率为65.45%(72/110),相比对照组的15.00%(15/100)较高,差异有统计学意义(P<0.05);且研究组ST-T改变、左心室高电压、窦性心律失常、期前收缩人数占比分别为24.55%(27/110)、21.82%(24/110)、10.00%(11/110)、6.36%(7/110),相比对照组的6.00%(6/100)、4.00%(4/100)、0.00%(0/100)、0.00%(0/100)较高,差异有统计学意义(P<0.05)。饮酒史时间<10年患者心电图异常发生率为35.29%(12/34),相比饮酒史时间≥10年患者的78.95%(60/76)较低,差异有统计学意义(P<0.05)。日饮酒量<300 g患者心电图异常率为69.39%(34/49),相比日饮酒量≥300 g患者的62.30%(38/61),差异无统计学意义(P>0.05)。经多因素Logistic回归分析可得:饮酒史时间≥10年是酒精依赖患者心电图改变的独立危险因素,差异有统计学意义(P<0.05)。结论酒精依赖患者心电图存在明显的异常,且长期饮酒是导致心电图改变的独立危险因素,值得临床重点关注。

Objective To study the changes of electrocardiogram in patients with alcohol dependence and analyze the related risk factors.Methods A total of 110 patients with alcohol dependence admitted to our hospital from April 2017 to April 2019 were selected for the study and recorded as the study group.In addition,100 normal persons who underwent physical examination in the hospital during the same period were taken as the control group.Compare and analyze the electrocardiogram changes of the two groups of people(mainly covering ST-T changes,left ventricular high voltage,sinus arrhythmia,pre-systolic contraction and conduction block,etc.),and analyze the changes in the history of drinking history and daily drinking volume on the electrocardiogram The impact of multi-factor logistic regression analysis.Results The abnormal incidence rate of ECG in the study group was 65.45%(72/110),which was higher than that in the control group(15.00%(15/100),the difference was statistically significant(P<0.05);and the ST-T changes,left ventricular high voltage,and the proportions of sinus arrhythmias and pre-systole were 24.55%(27/110),21.82%(24/110),10.00%(11/110),6.36%(7/110),compared with the control group 6.00%(6/100),4.00%(4/100),0.00%(0/100),and 0.00%(0/100)were higher,the difference was statistically significant(P<0.05).The incidence of abnormal electrocardiogram in patients with drinking history of less than 10 years was 35.29%(12/34),which was lower than that of patients with drinking history of more than 10 years of 78.95%(60/76),the difference was statistically significant(P<0.05).The abnormal rate of electrocardiogram in patients with daily alcohol consumption<300g was 69.39%(34/49),which was not significantly different from 62.30%(38/61)in patients with daily alcohol consumption≥300g,the difference was not statistically significant(P>0.05).Through multivariate logistic regression analysis,it can be obtained that the drinking history≥10 years is an independent risk factor for the change of electrocardiogram in patients with alcohol dependence,the difference was statistically significant(P<0.05).Conclusion There are obvious abnormalities in the electrocardiogram of alcohol dependent patients,and long-term drinking is an independent risk factor that leads to changes in electrocardiogram,which deserves clinical attention.