松岗地区9 346例孕产妇乙肝、丙肝、梅毒、艾滋病感染情况分析

Analysis of 9346 Pregnant Women with Hepatitis B,C,Syphilis and AIDS in Songgang

目的探讨松岗地区9346例孕产妇乙肝、丙肝、梅毒、艾滋病感染情况,以便为优生提供咨询指导和干预指导。方法选取2019年1—8月于该院妇产科就诊的9346例早期妊娠孕妇血清标本,采用酶联免疫法(ELISA)检测乙肝抗原(HBsAg)、丙肝抗体(HCV-Ab)、艾滋病病毒抗体(HIV-Ab),采用TRUST试验检测梅毒抗体。统计不同检测项目在不同年龄段的分布情况及治疗诊断情况,评价感染分布情况及治疗状况。结果松岗地区孕产妇HBsAg、HCV-Ab、TRUST、HIV-Ab阳性率分别为9.90%、0.13%、0.41%、0.01%,HBsAg在20岁以下、20~34岁之间、35岁以上年龄段的阳性率检出率分别为6.67%、10.13%、11.75%,各年龄段对比差异有统计学意义(P<0.05),其余各检测项目年龄分布情况对比差异无统计学意义。感染乙肝、丙肝、梅毒、艾滋病的孕产妇在产前(包括婚前、孕前、孕期)确诊者79.46%、83.33%、60.52%、100.00%,孕产妇开始治疗孕周晚于28周者27.35%、25.00%、47.37%、0.00%;规范用药比例为88.22%、91.67%、81.58%、100.00%。结论不同年龄段孕产妇早期感染性疾病的检测和治疗对于疾病的预防、传播具有重要意义,早期控制传播,提高优生优育。

Objective To investigate the infection of hepatitis B,hepatitis C,syphilis and AIDS in 9346 pregnant women in Songgang area in order to provide counseling and intervention guidance for eugenics.Methods Serum samples of 9346 early pregnancy pregnant women who were treated in the Obstetrics and Gynecology Department of our hospital from January to August 2019 were selected to detect hepatitis B antigen(HBsAg),hepatitis C antibody(HCV-Ab)by enzyme-linked immunoassay(ELISA),AIDS virus antibody(HIV-Ab),using TRUST test to detect syphilis antibody.Count the distribution of different test items in different age groups and the diagnosis of treatment,and evaluate the distribution of infection and treatment.Results The positive rates of HBsAg,HCV-Ab,TRUST and HIV-Ab in pregnant women in Songgang area were 9.90%,0.13%,0.41%and 0.01%respectively.HBsAg was under 20 years old,between 20-34 years old and over 35 years old,the detection rates of the positive rates of the segments were 6.67%,10.13%,and 11.75%respectively.There was a statistically significant difference between the age groups(P<0.05),and there was no statistically significant difference in the age distribution of the other test items.79.46%,83.33%,60.52%,100.00%of the pregnant women who were infected with hepatitis B,C,syphilis,and AIDS are diagnosed before delivery(including pre-marriage,pre-pregnancy,and pregnancy).27.35%,25.00%,47.37%and 0.00%of women who started treatment later than 28 weeks of gestation;normative medication rates were 88.22%,91.67%,81.58%,100.00%.Conclusion The detection and treatment of early infectious diseases of pregnant women of different ages are of great significance for the prevention and spread of the disease,early control of the spread and improvement of eugenics and postnatal care.