隔蒜灸联合化疗治疗气阴两虚型肺结核临床研究

Clinical Study on Garlic Partitioned Moxibustion Combined with Chemotherapy in the Treatment of Tuberculosis with Qi-Yin Deficiency Syndrome

目的:观察隔蒜灸联合化疗治疗气阴两虚型肺结核的临床疗效。方法:将73例气阴两虚型肺结核患者按照随机数字表法分为观察组37例和对照组36例。对照组给予常规抗结核药物治疗,观察组在对照组的基础上联合隔蒜灸治疗。比较两组患者的临床疗效及治疗前后中医证候评分、痰菌转阴率、胸部CT病灶变化、健康调查简表(the MOS item short from health survey,SF-36)生活质量量表评分变化情况。结果:两组患者治疗后中医证候积分低于本组治疗前,且观察组治疗后低于对照组治疗后,差异具有统计学意义(P<0.05)。对照组有效率为77.78%,观察组有效率为94.59%,两组患者有效率比较,差异具有统计学意义(P<0.05)。治疗1个月后,观察组痰菌转阴及肺部病灶吸收例数高于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后SF-36量表评分高于本组治疗前,且观察组治疗后高于对照组治疗后,差异具有统计学意义(P<0.05)。结论:隔蒜灸联合化疗治疗气阴两虚型肺结核,能够改善患者中医证候及生活质量,提高痰菌转阴率,加速肺部病灶的吸收速度。

Objective:To observe the clinical curative effect of garlic partitioned moxibustion combined with chemotherapy drugs on tuberculosis with qi-yin deficiency syndrome.Methods:A total of 73 patients with tuberculosis of qi-yin deficiency syndrome were randomly divided into the observation group with 37 cases and the control group with 36 cases.The control group was given conventional anti-tuberculosis drug treatment,and the observation group was additionally treated with garlic partitioned moxibustion on the basis of the control group.The clinical efficacy,TCM syndrome score,sputum negative conversion rate,chest CT lesion changes,and the MOS item short from health survey(SF-36) quality of life scale score were compared between the two groups before and after treatment.Results:After the treatment,TCM syndrome score of either of the two groups was lower than that before the treatment,and the TCM syndrome score of the observation group was lower than that of the control group,the difference was statistically significant(P<0.05).The effective rate of the control group was 77.78%,and that of the observation group was 94.59%.The difference was statistically significant(P<0.05).After one month of treatment,the numbers of sputum bacteria turning negative and pulmonary focus absorption in the observation group were higher than those in the control group,and all the differences were statistically significant(P<0.05).The SF-36 scale score of either of the two groups after treatment was higher than that of the same group before treatment,and the above index of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion:In terms of tuberculosis with qi-yin deficiency syndrome,garlic partitioned moxibustion can improve the TCM syndrome of patients,enhance the negative conversion rate of sputum bacteria,accelerate the absorption speed of lung lesions,and improve the quality of life of patients.