危重新生儿部分静脉营养治疗的应用与临床研究

Application and Clinical Study of Partial Intravenous Nutrition in Critically Ill Newborns

目的研究部分静脉营养在为重新生儿治疗中的效果及影响。方法随机选取本院新生儿科重症监护室2017年6月—2019年8月期间收治危重新生儿共74例设为研究对象,开展回顾性治疗研究。根据患儿家属是否同意接受部分静脉营养治疗分组,其中对照组、研究组样本量均为37例。对照组接受基础营养干预,研究组接受部分静脉营养干预。对比两组患儿营养干预前后体质量变化情况、临床治疗指标及并发症发生率。结果两组患儿入院时其体质量均数组间对比,差异无统计学意义,P>0.05;经不同模式营养干预后,两组患儿体质量均有所增加,相较对照组,研究组患儿实施营养干预后的总增加体质量及每日体质量增加均数均明显较高,且研究组患儿入院后NICU治疗时间、体质量下降时长、总治疗时间及并发症发生率降低明显,新生儿治愈率提升显著,P<0.05。结论部分静脉营养支持措施在危重新生儿治疗中的应用,可有效满足新生儿早期发育营养需求,并在确保其正常成长发育同时,促进自身病情缓解、恢复,应用效果显著。

Objective To study the effect and impact of partial intravenous nutrition in the treatment of severe neonates.Methods A total of 74 cases of critically ill neonates admitted in our hospital's neonatal intensive care unit from June 2017 to August 2019 were randomly selected as research subjects and retrospective treatment studies were conducted.According to whether the family members of the children agreed to receive partial intravenous nutrition therapy,the sample size of the control group and the study group was 37 cases.The control group received basic nutrition intervention,and the study group received partial intravenous nutrition intervention.The body weight changes,clinical treatment indicators,and complication rates of the two groups of children were compared before and after nutritional intervention.Results There was no significant difference in the comparison of body weight between the two groups of patients when they were admitted to hospital,P>0.05;after different types of nutritional intervention,the body weight of the two groups of patients increased,compared with the control group and the study group.The total increase in body weight and the average daily increase in body weight after nutritional intervention were significantly higher in the children,and the duration of the NICU treatment,the length of the decrease in body weight,the total treatment time,and the incidence of complications decreased in the study group.Obviously,the cure rate of newborns was significantly improved,P<0.05.Conclusion The application of some intravenous nutrition support measures in the treatment of critically ill neonates can effectively meet the nutritional needs of early neonatal development,and at the same time ensure their normal growth and development,promote the relief and recovery of their own conditions,and the application effect is significant.