艾滋病相关腹部淋巴瘤的临床特征与CT表现分析

Clinical and CT findings of AIDS-related abdominal lymphoma

目的探讨艾滋病相关腹部淋巴瘤的临床特征及CT表现,提高对艾滋病相关性腹部淋巴瘤的认识,为临床诊断及治疗提供依据。方法回顾性分析39例经病理证实艾滋病相关腹部淋巴瘤患者的临床特征及CT表现。结果39例艾滋病相关腹部淋巴瘤中霍奇金淋巴瘤1例,非霍奇金淋巴瘤38例,主要表现为多发淋巴结肿大,结外病变发生率较高(27/39,69.23%),结外病变中受累脏器包括肝脏11例,胰腺及胃各8例,脾脏、肠管及肾上腺各4例,肾脏3例,膀胱、子宫及睾丸各2例,前列腺1例。病灶多表现为密度减低软组织肿块,常堆积融合成团块状,瘤体中央易发生液化坏死为其主要特点。结论艾滋病相关腹部淋巴瘤以非霍奇金淋巴瘤为主,具有高侵袭性,广泛累及腹部淋巴结及淋巴结以外器官,淋巴结以外病变发生率高,CT表现具有一定特征性,结合临床表现,有利于提高诊断符合率。

Objective To explore the clinical characteristics and CT findings of AIDS-related abdominal lymphoma,enhance the understanding of AIDS-related abdominal lymphoma,and provide evidence for clinical diagnosis and treatment.Methods The clinical characteristics and CT findings of 39 patients with AIDS-related abdominal lymphoma confirmed by pathology were retrospectively analyzed.Results 1 of 39 cases of HIV/AIDS with abdominal lymphoma was associated with Hodgkin's lymphoma,and the other 38 cases were non-hodgkin's lymphoma cases.The main finding is the presence of multiple enlarged lymph nodes with high rate of extra-lymph node involvement(27/39,69.23%).All the extra-lymph node involvements include liver(n=11),pancreas and stomach(both n=8),spleen,intestines,and adrenal gland(n=4),kidney(n=3),bladder,uterus and testes(all n=2),and prostate gland(n=1).The lesions were mostly manifested as soft tissue masses with reduced density,often piled or fused into masses,with central liquefaction and necrosis.Conclusion AIDS-related abdominal lymphoma is mainly non-Hodgkin's lymphoma,which is highly invasive,extensively involving abdominal lymph nodes and organs other than lymph nodes,and has a high incidence of extra-lymph node involvement.CT findings were characteristic to some extent,and if combined with clinical manifestations,could improve the diagnostic match rate.