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血清NGAL在胃癌患者不同病理参数下的水平及临床应用研究 被引量:2

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摘要 目的通过对胃癌患者血清中性粒细胞明胶酶相关载脂蛋白(NGAL)水平与胃癌不同病理参数之间的相关性分析,探讨NGAL在胃癌早期诊断及预后判断中的临床意义。方法选取潍坊市肿瘤医院2019年7月至2019年12月接诊的68例胃癌患者作为观察组,另选取同期该院体检健康者71例作为对照组。使用增强免疫比浊法对NGAL水平进行检测。结果对照组血清NGAL水平低于观察组,差异有统计学意义(P<0.05)。观察组中无远处脏器转移患者血清NGAL水平低于有远处脏器转移患者,差异有统计学意义(P<0.05);TNM分期Ⅲ+Ⅳ期患者血清NGAL水平高于TNM分期Ⅰ+Ⅱ期患者,差异有统计学意义(P<0.05);无淋巴结转移患者血清NGAL水平低于有淋巴结转移的患者,差异有统计学意义(P<0.05)。结论血清NGAL水平与胃癌的发生和进展相关,在胃癌早期诊断及预后判断中有重要的临床应用价值。
出处 《检验医学与临床》 CAS 2020年第19期2886-2888,共3页 Laboratory Medicine and Clinic
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