阴道用活性杆菌胶囊治疗妊娠期细菌性阴道病对预防早产的临床观察

Clinical observation on the prevention of preterm delivery by the treatment of bacterial vaginosis during pregnancy with Vaginal Active Bacilli Capsules

目的探讨阴道用活性杆菌胶囊治疗妊娠期细菌性阴道病(BV)对预防早产的临床效果。方法选取2018年1月~2019年9月我院收治的100例妊娠期BV患者作为研究对象,采用随机数字表法将其分为对照组和观察组,每组各50例。对照组患者采用常规治疗,观察组患者采用阴道用活性杆菌胶囊治疗。两组患者均治疗10 d,比较两组患者的胎膜早破发生情况、疗效及不良妊娠结局。结果观察组的胎膜早破发生率低于对照组,差异有统计学意义(P<0.05);观察组的总有效率高于对照组,差异有统计学意义(P<0.05);观察组的不良妊娠结局总发生率低于对照组,差异有统计学意义(P<0.05)。结论阴道用活性杆菌胶囊治疗妊娠期BV对预防早产有积极的效果,能够降低胎膜早破发生率,提高治疗总有效率,减少流产、早产、新生儿窒息等不良妊娠结局的发生,有较高的应用价值。

Objective To investigate the clinical effect of Vagina Active Bacilli Capsules in the treatment of bacterial vaginosis(BV)during pregnancy on preterm delivery.Methods A total of 100 patients with BV during pregnancy recruited in our hospital from January 2018 to September 2019 were selected as the study objects and divided into control group and observation group with 50 cases in each group by random number table method.The patients in the control group were treated with conventional therapy.The patients in the observation group were treated with Vaginal Active Bacilli Capsules.All patients were treated for 10 days.The premature rupture of membranes occurred,curative effect and adverse pregnancy outcome in the two groups were compared.Results The incidence of premature rupture of membranes in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).The total incidence of adverse pregnancy outcomes in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The treatment of BV during pregnancy with Vagina Active Bacilli Capsules has a positive effect on the prevention of preterm delivery,and can reduce the incidence of premature rupture of membranes,improve the total effective rate of treatment,reduce the incidence of abortion,preterm delivery,neonatal asphyxia,etc.,and has a high application value.