片剂生产工艺常见问题分析及解决办法

Common Problem Analysis and Solving Methods of Tablet Manufacturing Technique

片剂是固体制剂中应用最广泛的剂型。为提升片剂生产工艺水平,促进制药行业的发展,指出了片剂生产工艺中制粒、压片、包衣工序中的常见问题,如裂片、松片、黏冲、拉冲、黏片、表面粗糙、架桥、包衣膜剥落、包衣片颜色不均匀等,提出了相应的解决办法。

Tablet is the most common applied dosage form of solid preparation.In order to improve tablet manufacturing technique level,and to promote the development of pharmaceutical industry,the research points out the common problems in pelletizing,tabletting and coating in tablet manufacturing technique,such as shred,loosing,viscosity,sticky,rough surface,bridging the hole,coating film peeling off and imbalanced coating tablet color,ect.,and proposes related solving problems.