糖尿病肾脏病病理特征与预后相关性的研究进展

Progress in research on correlation between pathological characteristics and prognosis of diabetic kidney disease

糖尿病肾脏病作为糖尿病的主要并发症之一,现已成为导致终末期肾病的主要原因。蛋白尿和血肌酐是目前判断糖尿病肾脏病发生及预后的主要临床指标,然而在敏感性及特异性上均存在不足。肾脏病理仍然是诊断糖尿病肾脏病的金标准,并且与糖尿病脏肾病的临床表现、预后相关性更强。本文就近年来国内外对于糖尿病肾脏病患者的病理特征与临床预后的相关性研究进行综述。

As one of the major complications of diabetes,diabetic kidney disease is the leading cause for end-stage renal failure.Proteinuria and serum creatinine are still the main clinical indicators for judging the occurrence and prognosis of diabetic kidney disease,but there are deficiencies in sensitivity and specificity.Renal pathology is still the gold standard for the diagnosis of diabetic kidney disease,and is more relevant to the clinical manifestations and prognosis of diabetic kidney disease.This review aims to summarize recent studies at home and abroad on the correlation between pathological features and clinical prognosis in patients with diabetic kidney disease.