蓝光照射联合茵陈蒿汤加减治疗重症黄疸45例

Clinical Curative Effect of Blue Light Irradiation Combined Modified Yinchenhao Decoction in the Treatment of 45 Patients with Severe Jaundice

目的:观察蓝光照射联合茵陈蒿汤加减治疗重症黄疸患儿的临床疗效。方法:将以重症黄疸入院的90例患儿,随机分为对照组和治疗组,每组45例。两组均采用蓝光照射治疗,治疗组在对照组基础上加用茵陈蒿汤加减治疗。观察两组治疗前后血清总胆红素、心肌酶水平,并观察不良反应发生情况。结果:治疗后治疗组血清总胆红素、心肌酶水平明显低于对照组,差异具有统计学意义(P<0.05);治疗组不良反应发生率为8.88%,显著低于对照组的17.78%,差异具有统计学意义(P<0.05)。结论:采用蓝光照射联合茵陈蒿汤加减治疗重症黄疸患儿效果优于单一蓝光照射治疗,且安全性较好,部分患儿避免了换血治疗。

Objective:To observe the clinical curative effect of blue light irradiation combined modified Yinchenhao decoction in the treatment of severe jaundice.Methods:90 Patients with severe jaundice were randomly divided into control group(45 patients)and treatment group(45 patients).The control group was treated with blue light irradiation.The treatment group was treated with blue light irradiation combined modified Yinchenhao decoction.The changes of serum total bilirubin(TSB)and myocardial enzymes were observed before and after treatment,and the adverse reactions were observed.Results:The levels of TSB and myocardial enzymes in the treatment group were significantly lower than those in the control group after treatment,and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the treatment group(8.88%)was significantly lower than that in the control group(17.78%),the difference was statistically significant(P<0.05).Conclusion:The blue light irradiation combined modified Yinchenhao decoction in the treatment of severe jaundice is better than that of single blue light irradiation,and the safety is good,some patients avoid exchange transfusion treatment.