瑞舒伐他汀联合氯吡格雷强化治疗急性心肌梗死的效果观察

Effects of risuvastatin combined with clopidogrel in the treatment of acute myocardial infarction

目的:探讨瑞舒伐他汀联合氯吡格雷强化治疗急性心肌梗死的临床效果。方法:抽取2017年5月至2019年5月威海市立第三医院收治的急性心肌梗死患者100例为研究对象,根据临床治疗方案将其分为对照组与观察组。对照组接受临床常规治疗,观察组在临床常规治疗基础上联合应用氯吡格雷、瑞舒伐他汀治疗。比较分析两组患者的治疗效果。结果:观察组治疗总有效率为96.00%(48/50),高于对照组的84.00%(32/50)(P<0.05)。治疗后,观察组B型利钠肽、左心射血分数、超敏C-反应蛋白及同型半胱氨酸指标均优于对照组(P<0.05)。观察组再梗死发生率(4.00%,2/50)及死亡率(2.00%,1/50)低于对照组(14.00%,7/50;10.00%,5/50),P均<0.05。结论:应用氯吡格雷、瑞舒伐他汀强化治疗心肌梗死患者,能有效改善患者症状、心功能,改善超敏C-反应蛋白等指标。

Objective To investigate the effects of risuvastatin combined with clopidogrel in the treatment of acute myocardial infarction.Methods A total of 100 patients with myocardial infarction admitted to Weihai Third Municipal Hospital from May 2017 to May 2019 were selected as the research objects.According to the clinical treatment plans,selected patients were divided into the control group and observation group.The control group received clinical routine treatment,and the observation group was treated with clopidogrel and rosuvastatin based on the routine treatment.The treatment effects of the two groups were compared and analyzed.Results The total effective rate of clinical treatment in the observation group was 96.00%(48/50),significantly higher than the 84.00%(32/50)in the control group(P<0.05).The levels of B-type natriuretic protein,left ventricular ejection fraction,high-sensitivity C-reactive protein and hemocyanin in the observation group were significantly better than those in the control group(P<0.05).And the reinfarction rate and case fatality rate in the observation group(4.00%,2/50;2.00%,1/50)were significantly lower than those in the control group(14.00%,7/50;10.00%,5/50),all P<0.05.Conclusions Clopidogrel and rosuvastatin in the treatment of acute myocardial infarction can effectively improve the symptoms,heart function,and ameliorate related indexes,for example high-sensitivity C-reactive protein.