颈动脉分叉夹角、ICA/CCA参数与颅内动脉粥样硬化的关系

Relationship between carotid bifurcation angle,ICA/CCA parameters and intracranial atherosclerosis

目的分析颈动脉分叉夹角、颈总动脉/颈内动脉(ICA/CCA)参数与颅内动脉粥样硬化的关系。方法抽取2018年10月至2019年10月驻马店市中心医院收治的颅内动脉粥样硬化患者90例为研究组,同期选取50例正常人为对照组。并根据颅内动脉粥样硬化程度,将90例患者分为轻度组、中度组、重度组,比较各组患者颈动脉分叉夹角、ICA/CCA参数。结果研究组患者舒张期末期流速(EDV)、收缩期峰值流速(PSV)低于对照组,阻力指数(RI)、颈内动脉PSV/颈总动脉PSV高于对照组(P<0.05);研究组患者颈总动脉分叉角(CABA)、颈内动脉角(ICAA)高于对照组(P<0.05);重度组患者PSV、EDV低于中度组、轻度组,RI、颈内动脉PSV/颈总动脉PSV高于中度组、轻度组(P<0.05);中度组患者PSV、EDV低于轻度组,RI、PSV颈内动脉/PSV颈总动脉高于轻度组(P<0.05);重度组ICAA、CABA高于中度组、轻度组(P<0.05);颅内动脉粥样硬化与动脉分叉夹角、RI、颈内动脉PSV/颈总动脉PSV呈负相关,与PSV、EDV呈正相关(P<0.05)。结论颅内动脉粥样硬化与动脉分叉夹角、RI、颈内动脉PSV/颈总动脉PSV呈负相关,与PSV、EDV呈正相关。

Objective To investigate the relationship between carotid bifurcation angle,internal carotid artery/common carotid artery(ICA/CCA)parameters and intracranial atherosclerosis.Methods A total of 90 patients with intracranial atherosclerosis(study group)and 50 healthy individuals(control group)in Zhumadian Central Hospital from October 2018 to October 2019 were enrolled.The 90 patients were further divided into three subgroups such as mild group,moderate group and severe group according to the degree of intracranial atherosclerosis,The angle of carotid bifurcation and ICA/CCA parameters in each group were compared.Results The end diastolic velocity(EDV)and peak systolic velocity(PSV)in the study group were lower than those in the control group,resistance index(RI),internal carotid artery PSV/common carotid artery PSV were higher than those of control group(P<0.05);the angle of common carotid artery bifurcation(CABA)and internal carotid artery angle(ICAA)in the study group were higher than those in the control group(P<0.05).PSV and EDV in severe group were lower than those in moderate group and mild group,RI and internal carotid artery PSV/common carotid artery PSV were higher than those in moderate group and mild group(P<0.05);PSV and EDV in moderate group were lower than those in mild group,RI and internal carotid artery PSV/common carotid artery PSV were higher than those in mild group(P<0.05);ICAA and CABA in severe group were higher than moderate and mild groups(P<0.05).Intracranial atherosclerosis was negatively correlated with arterial bifurcation angle,RI,and PSV ICA/PSV CCA,and positively correlated with PSV and EDV(P<0.05).Conclusions Intracranial atherosclerosis is negatively related to arterial bifurcation angle,RI,and internal carotid artery PSV/common carotid atery PSV,and positively correlated with PSV and EDV.