老年患者全髋关节置换术后恶心呕吐的危险因素

Risk factors for nausea and vomiting after total hip arthroplasty in elderly patients

本研究为单中心、大样本病例对照研究。收集自2013年6月至2019年5月行单侧全髋关节置换术老年患者1106例的病历数据:患者一般情况、并存疾病、围术期用药、术中血压、术后转归等项目的指标水平。根据术后24 h期间是否发生恶心呕吐,将患者分为术后恶心呕吐(PONV)组和未发生PONV组,采用logistic回归分析法确定PONV发生的危险因素。PONV发生率为11.03%。女性、术中使用地佐辛、术中低血压(持续时间>3 min或累计时间>6 min)是PONV的独立危险因素,而股骨颈骨折、术中使用地塞米松是其保护性因素。

This study was a single-center large-sample case-control study.Data of 1106 elderly patients who underwent unilateral total hip arthroplasty from June 2013 to May 2019 were collected,including items such as patient′s baseline characteristics,comorbidities,perioperative medication,intraoperative blood pressure,and postoperative outcomes.Patients were divided into postoperative nausea and vomiting(PONV)group and non-PONV group according to whether nausea and vomiting occurred within 24 h after operation.Logistic regression analysis was used to determine the risk factors for PONV.The incidence of PONV was 11.03%.Female,intraoperative use of dezocine,and intraoperative hypotension(duration>3 min or cumulative time>6 min)are independent risk factors for PONV,while femoral neck fractures and intraoperative use of dexamethasone are protective factors.