芙汭皮肤膏手护理抑菌效果

Antibacterial Effect of FORENEE skin ointment on hand care

目的比较医护人员使用某皮肤清洗液洗手后使用芙汭皮肤膏对手部细菌菌落计数、皮肤屏障功能的影响以及使用者的主观评价,探讨更适用于医务工作者的手消毒、手护理方法。方法选择2020年3-6月北京大学第三医院门诊医护人员作为监测对象,并随机分为试验组和对照组,每组60人次,其中医生和护士分别为29人次和31人次。监测对象均按七步洗手法洗手1 min,用无菌擦手纸擦干双手。试验组洗手后使用芙汭皮肤膏1 g均匀涂抹双手背与手掌,对照组不使用任何护手霜。采集两组洗手后即刻、洗手后30 min的手部样本,进行细菌培养及菌落计数。分别在洗手前、洗手后30 min对手部行皮肤屏障功能检测,同时收集监测对象洗手后30 min手部舒适度的主观评价。结果试验组与对照组医护人员洗手后即刻菌落计数比较差异无统计学意义,洗手后30 min试验组菌落计数显著低于对照组(P=0.001);试验组与对照组洗手前角质层含水量(Stratum corneum hydration,SCH)及经皮肤水分丢失(transepidermalwater loss,TEWL)值比较差异无统计学意义,洗手后30 min试验组SCH高于对照组,TEWL低于对照组(P<0.05);洗手后30 min试验组手部舒适度评分优于对照组(P<0.05)。结论洗手后使用芙汭皮肤膏可增强洗手后的抑菌效果,并可以帮助维护皮肤屏障功能,且在皮肤舒适度方面较好,可以作为手护理的一部分,在临床中推广应用。

OBJECTIVE To compare the effects of FORENEE skin ointment dressing on bacterial colony counts and skin barrier function of health care workers,analyze the users′objective evaluation and explore the hand disinfection and hand care measures suitable for the health care workers.METHODS From Mar 2020 to Jun 2020,the health care workers of outpatient department of Peking University Third Hospital were chosen as the monitoring subjects and randomly divided into the experimental group and the control group,with 60 subjects in each group,and there were 29 doctors and 31 nurses in each group.All of the subjects washed their hands for one minute according to the seven-step hand-washing method and dried their hands with sterile paper towels.The experimental group was treated with 1 g of FORENEE skin ointment dressing to the back and palm of both hands evenly,while the control group was not treated with any hand cream.The samples were collected from the hands of the subjects instantly after hand washing and after the hand washing for 30 min.The barrier function of hand skins was detected before the hand washing and after the hand washing for 30 min,meanwhile,the subjective assessment on the hands′comfort was collected from the monitoring subjects after the hand washing for 30 min.RESULTS There was no significant difference in the bacterial colony counts between the experimental group and the control group instantly after the hand washing,and the bacterial colony counts of the experimental group were significantly lower than those of the control group after the hand washing for the control group(P=0.001).There were significant differences in the stratum corneum hydration(SCH)and transepidermal water loss(TEWL)between the experimental group and the control group before the hand washing;the SCH of the experimental group was significantly higher than that of the control group after the hand washing for 30 min,and the TEWL of the experimental group was significantly significantly lower than that of the control group(P<0.05).The score of hands′comfort of the experimental group was significantly higher than that of the control group(P<0.05).CONCLUSION FORENEE skin ointment dressing can enhance the antibacterial effect after the hand washing and help to maintain the skin barrier function,and it is much better with the respect to the hands′comfort,as a part of hand care,it is worthy to be promoted in hospital.