奥美拉唑联合阿莫西林、甲硝唑对消化性溃疡进行治疗的临床效果

Clinical effect of omeprazole combined with amoxicillin and metronidazole on peptic ulcer

目的:研究治疗消化性溃疡过程中运用奥美拉唑联合阿莫西林、甲硝唑的临床效果。方法:研究地点为本院,时间为2018年11月至2019年10月,选定患有消化性溃疡的患者66例,分组时参照随机数字表法,研究组共计33例患者,行奥美拉唑联合阿莫西林、甲硝唑治疗,对照组共计33例患者,行雷尼替丁联合阿莫西林、甲硝唑治疗。结果:对比研究组及对照组临床数据,前者治疗总有效率明显更高,不良反应发生率明显更低,幽门螺杆菌清除率明显更高,差异存在统计学意义(P<0.05)。结论:治疗消化性溃疡过程中运用奥美拉唑联合阿莫西林、甲硝唑,效果确切。

Objective:To study the clinical effect of omeprazole combined with amoxicillin and metronidazole in the treatment of peptic ulcer.Methods:The study site was our hospital,and the time was from November 2018 to October 2019.66 patients with peptic ulcer were selected and divided into groups according to random number table.A total of 33 patients in the study group were treated with omeprazole combined with amoxicillin and metronidazole,while 33 patients in the control group were treated with ranitidine combined with amoxicillin and metronidazole.Results:Comparing the clinical data of the study group and the control group,the total effective rate of the former was significantly higher,the incidence of adverse reactions was significantly lower,and the clearance rate of Helicobacter pylori was significantly higher,and the differences were statistically significant(P<0.05).Conclusion:Omeprazole combined with amoxicillin and metronidazole is effective in treating peptic ulcer.