长葛市某蛋鸡场高致病性禽流感疫苗免疫效果分析

Analysis of immune effect of highly pathogenic avian influenza vaccine in an egg farm in Changge City

禽流感是由A型流感病毒引起的一种禽类传染病,疫苗免疫接种是预防禽流感最经济、有效的手段,为探讨高致病性禽流感疫苗的免疫效果,长葛市某蛋鸡场采用H5亚型禽流感三价灭活疫苗对17日龄鸡群进行首免,对55日龄鸡群进行二免,对124日龄鸡群进行三免,对鸡群免疫后的抗体水平进行了监测与分析。结果显示首免后39天,H5亚型Re-6抗体平均值(log2)达到3.9,二免后16天、32天、48天、63天鸡群H5亚型Re-6抗体平均值(log2)分别达到6.1、7.8、7.0、6.9,三免后9天、24天、39天鸡群H5亚型Re-6抗体平均值(log2)分别达到7.6、8.5、8.0。经过三次免疫之后,鸡群抗体值均达到较高水平,该养殖场的免疫程序对鸡群起到良好的免疫保护效果。

Avian influenza was a kind of avian infectious disease caused by influenza A virus,and vaccine active immunization was the most economical and effective means to prevent avian influenza.The first immunization was carried out against the 17-day-old chickens in an egg chicken field in Changge.The second immunization was carried out against the 55-day-old chickens.The third immunization was conducted against the 124-day-old chickens.The antibody level of H5 subtype avian influenza virus was monitored and analyzed.The results showed that the average value of Re-6 antibody(log2)of H5 subtype reached 3.9 on 39 days after the first immunization,6.1,7.8,7.0 and 6.9 on 16,32,48 and 63 days after the second immunization,and 7.6,8.5 and 8.0 on 9,24 and 39 days after the third immunization,respectively.The conclusion was that after three times of immunization,the antibody value of the chicken flocks reached a high level,and the immune program could play a good immune protection effect on the chicken.