急性肝衰竭诊治进展

Research progress on diagnosis and treatment of acute liver failure

急性肝衰竭(ALF)进展迅速,病死率高,目前尚无确定性治疗方法。ALF表现为肝功能失调、凝血障碍、肝性脑病等,可迅速发生多器官功能衰竭。近年来,ALF在早期识别与评估、重症加强治疗、人工肝以及急诊肝移植等方面取得了一定进展,患者的生存率也有所提高。该文对ALF近年的诊治进展进行了综述。

Acute liver failure(ALF)progresses rapidly and yields high mortality rate.At present,no definitive treatment is available for ALF.The clinical manifestations of ALF include hepatic dysfunction,coagulopathy and encephalopathy etc.,which can rapidly cause multiple organ failure.During recent years,certain progress has been made in the early diagnosis and evaluation,intensive care treatment,artificial liver and emergent liver transplantation for ALF.The survival rate of patients with ALF has been significantly improved.In this article,research progresses on the diagnosis and treatment of ALF were reviewed.