七氟烷与地氟烷用于小儿麻醉维持后苏醒质量的临床比较研究

Clinical Comparison of Sevoflurane and Desflurane in the Quality of Recovery after Anesthesia Maintenance in Children

目的:研究和比较七氟烷与地氟烷用于小儿麻醉维持后苏醒质量的临床效果差异。方法:选取笔者所在医院2018年9月-2020年2月临床收治的80例手术患儿为研究对象,随机将患儿分成研究组和对照组,各40例。对照组和研究组分别以七氟烷和地氟烷维持麻醉。对两组苏醒时间、血流动力学指标和不良反应发生情况进行观察和比较。结果:研究组出现睁眼或体动时间、出手术室时间和完全清醒时间均早于对照组,差异均有统计学意义(P<0.05);两组术中不同时间MBP和HR比较差异无统计学意义(P>0.05);研究组不良反应总发生率为10.00%,低于对照组的27.50%,差异有统计学意义(P<0.05)。结论:采用地氟烷进行小儿麻醉维持后患儿苏醒时间更早,不良反应控制更好,整体苏醒质量更高,值得在小儿麻醉临床实践中推广应用。

Objective:To further study and compare the clinical effect of Sevoflurane and Desflurane on the recovery quality of children after anesthesia maintenance.Method:From September 2018 to February 2020,80 cases of surgical children admitted to our hospital were randomly divided into the study group and the control group,40 cases in each group.The control group was given Sevoflurane for maintenance anesthesia,the study group was given desflurane for maintenance anesthesia.The recovery time,hemodynamic indexes and adverse reactions of the two groups were observed and compared.Result:The time of opening eyes or moving body,leaving operating room and fully awake in the study group were earlier than those in the control group,the differences were statistically significant (P<0.05).There was no significant difference between the two groups in MBP and HR indexes at different time (P>0.05).The total incidence of adverse reactions in the study group was 10.00%,lower than 27.50% in the control group,the difference was statistically significant (P<0.05).Conclusion:The use of Desflurane in children after maintenance of anesthesia,the recovery time is earlier,better adverse reaction control,the overall quality of recovery is higher.It is worthy of popularization and application in pediatric anesthesia clinical practice.