甲氧氯普胺、耳针联合艾灸对奥沙利铂化疗所致部分副作用效果

Effect of Metoclopramide,Ear Acupuncture and Moxibustion on Some Side Effects Caused by Oxaliplatin Chemotherapy

目的:探讨甲氧氯普胺、耳针联合艾灸对奥沙利铂化疗所致部分副作用的效果。方法:选定本院2016年9月-2019年1月收诊的64例胃肠道肿瘤患者,均采用奥沙利铂化疗。采用等距抽样法分为对照组(甲氧氯普胺,32例)与观察组(甲氧氯普胺+耳针+艾灸,32例)两组,比较两组胃肠道肿瘤患者的神经毒性Ⅱ~Ⅳ级发生率、恶心呕吐率及满意率。结果:观察组神经毒性Ⅱ~Ⅳ级发生率(12.50%)低于对照组(P<0.05);观察组恶心呕吐率(3.13%)低于对照组(P<0.05);观察组总满意率(90.63%)高于对照组(P<0.05)。结论:应用甲氧氯普胺、耳针联合艾灸后,可提高胃肠道肿瘤患者的诊治满意率,降低奥沙利铂化疗所致神经毒性、恶心呕吐的发生率,值得使用推广。

Objective:To investigate the effect of Metoclopramide,ear acupuncture and moxibustion on some side effects caused by Oxaliplatin chemotherapy.Method:Sixty-four patients with gastrointestinal tumors admitted in our hospital from September 2016 to January 2019 were selected for chemotherapy with Oxaliplatin.The equidistant sampling method was used to divide the control group (Metoclopramide,32 cases) and the observation group (Metoclopramide+ear acupuncture+moxibustion,32 cases) into two groups,and compared the two groups of gastrointestinal tumor patients of the incidence of neurotoxicity grade Ⅱ to Ⅳ,nausea and vomiting rate and satisfaction rate.Result:The incidence of neurotoxicity grade Ⅱ to Ⅳ (12.50%) in the observation group was lower than that in the control group (P<0.05);the nausea and vomiting rate in the observation group (3.13%) was lower than that in the control group (P<0.05);the overall satisfaction rate in the observation group (90.63%) was higher than the control group (P<0.05).Conclusion:The application of Metoclopramide,ear acupuncture and moxibustion can improve the satisfaction rate of patients with gastrointestinal tumors and reduce the incidence of neurotoxicity and nausea and vomiting caused by Oxaliplatin chemotherapy.It is worthy of promotion.