摘要
基于强迫振荡技术(forced oscillation technology,FOT)的肺功能检查对早期发现气道疾病具有重要意义,但如何提高及评估阻抗测量系统的辨识精度仍是当前难点。针对此问题,本研究以音圈电机为振荡源构建阻抗测量系统,通过对3D打印的气道模型进行阻抗测量,分析了阻抗与支气管堵塞程度的敏感性和分布关系。结果表明,基于音圈电机的阻抗测量系统能够检测到气道模型两个以上小孔径(0.8 cm)截面积堵塞的阻抗变化,并且阻抗与堵塞端口数量近似呈指数分布关系。本研究采用气道模型来量化评估了阻抗测量系统的辨识精度,推进了FOT技术在气道阻塞程度和阻塞部位评估的研究。
Pulmonary function testing based on forced oscillation technology(FOT)has great significance in the early detection of airway diseases,but how to improve and evaluate the identification accuracy of the impedance measurement system is still difficult.In view of the above problems,we builded an impedance measurement system with a voice coil motor oscillation source.By measuring the impedance of the 3D printed airway model,the sensitivity and distribution relationship between the measured impedance and the degree of bronchial obstruction were analyzed.The results showed that the impedance measurement system based on the voice coil motor could detect the impedance change of the cross-sectional area of more than two small apertures(0.8 cm)in the airway model,the impedance and the number of blocked ports were approximately exponentially distributed.Using the airway model to quantitatively evaluate the identification accuracy of the impedance measurement system,can advance the research of FOT in estimating the degree of airway obstruction and the location of the obstruction.
作者
贲鸿伟
车波
周婷
刘磊
邓林红
BEN Hongwei;CHE Bo;ZHOU Ting;LIU Lei;DENG Linhong(Institute of Biomedical Engineering and Health Science,Changzhou University,Changzhou 213164,China;School of Information Science and Engineering,Changzhou University,Changzhou 213164)
出处
《生物医学工程研究》
2020年第3期277-281,共5页
Journal Of Biomedical Engineering Research
基金
国家自然科学基金资助项目(11532003,31670950)。
关键词
强迫振荡技术
音圈电机
呼吸阻抗
辨识精度
气道模型
Frequency forced oscillation technique
Voice coil motor
Respiratory impedance
Identification accuracy
Airway model