扣带回癫痫的临床研究进展

Clinical research progress of cingulate epilepsy

扣带回癫痫(CE)以往被认为是额叶癫痫的一种亚型,其发病机制尚不十分清楚。与额叶癫痫相比,CE的发病年龄偏小,临床主要表现为额叶癫痫或(和)颞叶癫痫以及其他少见癫痫;脑电图异常放电表现多样;MRI检查多为正常。脑磁图、颅内脑电图、PET、图像后处理技术及多模态术前评估检查常显示扣带回结构和功能异常。常规抗癫痫药物治疗效果可能与病因有关,手术疗效明显,术后病理检查最常见的病理类型为局灶性皮质发育不良。为提高功能神经外科及神经内科医师对扣带回及扣带回癫痫的认识和理解,本文对扣带回癫痫的研究进展进行综述。

Cingulate epilepsy(CE)was previously considered as a subtype of frontal lobe epilepsy,and its pathogenesis is still not very clear.Compared with frontal lobe epilepsy,CE'sonset age is young and main clinical manifestations are similar to frontal lobe epilepsy or(and)temporal lobe epilepsy and other rare epilepsy.EEG abnormal discharge performances are diversified.MRI performance is usually negative,IEEG,PET,MEGand image post-processing technology and multimodal preoperative assessment often show abnormal structure and function of the cingulate.The curative effect of conventional antiepileptic drugs may be related to the cause of disease.The most common pathological type after operation is focal cortical dysplasia.In order to improve the understanding and understanding of cingulate cortex and cingulate epilepsy by functional neurosurgery and neurologist,this paper reviews the research progress of CE.