以癫痫为唯一首发症状的抗γ-氨基丁酸B型受体脑炎一例
摘要
抗γ-氨基丁酸B型(GABAB)受体脑炎属于一种少见的自身免疫性脑炎(Autoimmune encephalitis,AE)类型,临床表现以癫痫、精神行为异常、认知功能损害为主,多见于老年人,常伴有小细胞肺癌。本文报道一例抗GABAB受体脑炎青年女性患者的临床发病特点以及影像学等检查结果,以提高临床医师对该疾病的认识。
出处
《癫痫杂志》
2020年第5期464-466,共3页
Journal of Epilepsy
参考文献3
-
1中华医学会神经病学分会,中华医学会神经病学分会神经血管介入协作组.急性缺血性脑卒中早期血管内介入治疗流程与规范专家共识[J].中华神经科杂志,2017,50(3):172-177. 被引量：97
-
2关鸿志,崔丽英.抗体相关的中枢神经系统自身免疫性疾病:探索与挑战[J].中华神经科杂志,2019,52(2):81-84. 被引量：8
-
3Hong-Zhi Guan,Hai-Tao Ren,Xun-Zhe Yang,Qiang Lu,Bin Peng,Yi-Cheng Zhu,Xiao-Qiu Shao,Yong-Qiang Hu,Dong Zhou,Li-Ying Cui.Limbic Encephalitis Associated with Anti-y-aminobutyric Acid B Receptor Antibodies： A Case Series from China[J].Chinese Medical Journal,2015(22):3023-3028. 被引量：40
二级参考文献24
-
1Graus F, Saiz A, Lai M, Bruna J, Lopez F, Sabater L, et al. Neuronal surface antigen antibodies in limbic encephalitis: Clinical-immunologic associations. Neurology 2008;71:930-6.
-
2Graus F, Dalmau J. Paraneoplastic neurological syndromes. Curr Opin Neurol 2012;25:795-801.
-
3Lancaster E, Lai M, Peng X, Hughes E, Constantinescu R, Raizer J, et al. Antibodies to the GABA(B) receptor in limbic encephalitis with seizures: Case series and characterisation of the antigen. Lancet Neurol 2010;9:67-76.
-
4Hoftberger R, Titulaer MJ, Sabater L, Dome B, Rozsas A, Hegedus B, et al. Encephalitis and GABAB receptor antibodies: Novel findings in a new case series of 20 patients. Neurology 2013;81:1500-6.
-
5Jeffery OJ, Lennon VA, Pittock SJ, Gregory JK, Britton JW, McKeon A. GABAB receptor autoantibody frequency in service serologic evaluation. Neurology 2013;81:882-7.
-
6Billinton A, Ige AO, Wise A, White JH, Disney GH, Marshall FH, et al. GABA(B) receptor heterodimer-component localisation in human brain. Brain Res Mol Brain Res 2000;77:111-24.
-
7Lujan R, Shigemoto R. Localization of metabotropic GABA receptor subunits GABAB 1 and GABAB2 relative to synaptic sites in the rat developing cerebellum. Eur J Neurosci 2006;23:1479-90.
-
8Benarroch EE. GABAB receptors: Structure, functions, and clinical implications. Neurology 2012;78:578-84.
-
9Hainsworth JB, Shishido A, Theeler BJ, Carroll CG, Fasano RE. Treatment responsive GABA(B)-receptor limbic encephalitis presenting as new-onset super-refractory status epilepticus (NORSE) in a deployed U.S. soldier. Epileptic Disord 2014;16:486-93.
-
10Jarius S, Steinmeyer F, Knobel A, Streitberger K, Hotter B, Horn S, et al. GABAB receptor antibodies in paraneoplastic cerebellar ataxia. J Neuroimmunol 2013;256:94-6.
共引文献140
-
1唐姗姗,罗曦.自身免疫性脑炎患者血清免疫球蛋白水平与疾病转归的关系[J].中国实验诊断学,2023,27(9):1030-1033.
-
2郭琳,马莉,盛井香.心理干预在脑卒中吞咽障碍患者康复训练中的效果[J].心理月刊,2022(6):118-120. 被引量：1
-
3沙晶,艾山江·玉素甫江,玛依努尔·买买提,李红燕.复发性抗MOG抗体相关性视神经炎-脑脊髓炎一例[J].中国现代神经疾病杂志,2020(10):877-880. 被引量：1
-
4余年,林兴建,张燕芳,狄晴,石静萍.关于中国抗γ-氨基丁酸B受体脑炎患者叠加多种自身抗体的临床分析[J].脑与神经疾病杂志,2020(7):410-414. 被引量：1
-
5许海兵,沈孝翠,吉玉刚,辛春,温竞.FLAIR血管高信号与急性缺血性卒中低灌注强度比值相关性研究[J].临床放射学杂志,2020,39(11):2175-2180. 被引量：1
-
6杨明,郑灿文,高国佳.高档仿麂皮革基布生产工艺探讨[J].印染,2000,26(4):24-25.
-
7刘长广,王爱霞.单味虎杖应用于四肢骨折后期的治疗体会[J].中医外治杂志,2000,9(1):51-51. 被引量：1
-
8徐祖兵,曾芳芳,袁亚辉.急性缺血性卒中患者静脉溶栓后早期无改善:预测因素和对转归的影响[J].国际脑血管病杂志,2018,26(11):801-806. 被引量：4
-
9赵伟丽,林福虹,尹国明,郑纪平,李国丽,王迎春,乔小东,芦军,王洪权,崔其福,任海涛,关鸿志.8例自身免疫性脑炎的病例分析并文献复习[J].中风与神经疾病杂志,2016,33(10):927-931. 被引量：10
-
10卢节平,汤其强,汪莉,丁小灵.伴小细胞肺癌的抗γ氨基丁酸B受体脑炎1例报告及文献复习[J].中国神经精神疾病杂志,2016,42(12):755-756. 被引量：1
-
1王欧阳,高磊,何卫东.饲料硫酸铜超标所致猪中毒的诊治及预防[J].中国畜禽种业,2020,16(9):122-122. 被引量：2
-
2薛硕,周婧或,鞠卫萍.1例伴呼吸衰竭抗AMPA2受体抗体脑炎及文献复习[J].世界最新医学信息文摘,2020(49):217-218.
-
3Homayun Shahpesandy,Rosemary Mohammed-Ali,Ahmed Oladosu,Tarik AI-Kubaisy,Moses Anene,Umesh Sira Ramaiah.Anti-voltage-gated potassium channel complex antibody-mediated limbic encephalitis:a case report of a 53-yearold man admitted to intensive care psychiatric unit with psychotic mania[J].General Psychiatry,2020,33(4):241-244. 被引量：1
