双相情感障碍患者自杀意念与基因甲基化相关性的研究进展

Research progress on the relationship between suicidal ideation and gene methylation in patients with bipolar disorder

双相情感障碍是高致残性的重型精神障碍,具有很高的自杀率。近几年,多项研究显示基因甲基化与双相情感障碍患者自杀意念相关。现对近年来有关双相情感障碍患者自杀意念与基因甲基化相关性的研究进行归纳总结。

Bipolar disorder is a severe and highly crippling mental disorder with a high suicide rate.In recent years,many studies have shown that gene methylation is associated with suicidal ideation in patients with bipolar disorder.In this paper,the recent studies on the relationship between suicidal ideation and gene methylation in patients with bipolar disorder were summarized.